Search results
Results from the WOW.Com Content Network
PK/PD relationships can be described by simple equations such as linear model, Emax model or sigmoid Emax model. [5] However, if a delay is observed between the drug administration and the drug effect, a temporal dissociation needs to be taken into account and more complex models exist: [6] [7] Direct vs Indirect link PK/PD models
There are direct and indirect benefits of being the selective individual. [5] [6] [7] In most species, females are the choosy sex which discriminates among competitive males, [4] but there are several examples of reversed roles (see below).
Structural equation modeling (SEM) began differentiating itself from correlation and regression when Sewall Wright provided explicit causal interpretations for a set of regression-style equations based on a solid understanding of the physical and physiological mechanisms producing direct and indirect effects among his observed variables.
In statistics, path analysis is used to describe the directed dependencies among a set of variables. This includes models equivalent to any form of multiple regression analysis, factor analysis, canonical correlation analysis, discriminant analysis, as well as more general families of models in the multivariate analysis of variance and covariance analyses (MANOVA, ANOVA, ANCOVA).
Direct realism, also known as naïve realism, argues we perceive the world directly. In the philosophy of perception and philosophy of mind, direct or naïve realism, as opposed to indirect or representational realism, are differing models that describe the nature of conscious experiences; [1] [2] out of the metaphysical question of whether the world we see around us is the real world itself ...
The theory is based on the hypothesis that cooperation helps in transmitting underlying genes to future generations either through increasing the reproductive successes of the individual (direct fitness) or of other individuals who carry the same genes (indirect fitness). Direct benefits can result from simple by-product of cooperation or ...
Direct reciprocity was proposed by Robert Trivers as a mechanism for the evolution of cooperation. [1] If there are repeated encounters between the same two players in an evolutionary game in which each of them can choose either to "cooperate" or "defect", then a strategy of mutual cooperation may be favoured even if it pays each player, in the short term, to defect when the other cooperates.
The structures they form also form parts of complex protein signaling pathways. [7] In one respect, tight junctions play a generic role in cell signaling in that they may form a tight zip around cells, forming a barrier to stop even small, unwanted signalling molecules from getting between cells. [ 8 ]