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Avascular necrosis (AVN), also called osteonecrosis or bone infarction, is death of bone tissue due to interruption of the blood supply. [1] Early on, there may be no symptoms. [1] Gradually joint pain may develop, which may limit the person's ability to move. [1] Complications may include collapse of the bone or nearby joint surface. [1]
Necrotic bone does not undergo resorption; therefore, it appears relatively more opaque. Attempts at repair of ischaemic-damaged bone will usual occur in 2 phases. First, when dead bone abuts live marrow, capillaries and undifferentiated mesenchymal cells grow into the dead marrow spaces, while macrophages degrade dead cellular and fat debris ...
Coagulative necrosis occurs primarily in tissues such as the kidney, heart and adrenal glands. [6] Severe ischemia most commonly causes necrosis of this form. [8] Liquefactive necrosis (or colliquative necrosis), in contrast to coagulative necrosis, is characterized by the digestion of dead cells to form a viscous liquid mass. [7]
The condition is usually characterized by a sudden onset of knee pain, worse at night, or during weight-bearing such as standing or running. Nevertheless, it can also occur during rest or without any weight-bearing. About 94% of the cases affect the medial condyle of the femur. This is because the blood supply for the medial condyle is less ...
Dysbaric osteonecrosis or DON is a form of avascular necrosis where there is death of a portion of the bone that is thought to be caused by nitrogen (N 2) embolism (blockage of the blood vessels by a bubble of nitrogen coming out of solution) in divers. [1] Although the definitive pathologic process is poorly understood, there are several ...
Medical condition Osteochondritis dissecans A large flap lesion in the femur head typical of late stage Osteochondritis dissecans. In this case, the lesion was caused by avascular necrosis of the bone just under the cartilage. Pronunciation / ˌ ɒ s t i. oʊ k ɒ n ˈ d r aɪ t ɪ s ˈ d ɪ s ɪ k æ n z / Specialty Orthopedic surgery Osteochondritis dissecans (OCD or OD) is a joint disorder ...
Osteochondrosis is a family of orthopedic diseases of the joint that occur in children, adolescents and rapidly growing animals, particularly pigs, horses, dogs, and broiler chickens. They are characterized by interruption of the blood supply of a bone, in particular to the epiphysis , [ 1 ] followed by localized bony necrosis , [ 2 ] and later ...
Osteoradionecrosis (ORN) is a serious complication of radiation therapy in cancer treatment where radiated bone becomes necrotic and exposed. [1] ORN occurs most commonly in the mouth during the treatment of head and neck cancer, and can arise over 5 years after radiation. [2]