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There are several ways to measure glycated hemoglobin, of which HbA1c (or simply A1c) is a standard single test. [5] HbA1c is measured primarily to determine the three-month average blood sugar level and is used as a standard diagnostic test for evaluating the risk of complications of diabetes and as an assessment of glycemic control .
In the UK, the NHS's diabetes prevention programme Healthier You offers personalised face-to-face and digital services. [26] Assessment of the programme is ongoing, but based on the first 36,000 patients, it seems that those who complete the programme manage to reduce their blood sugar levels and lose weight.
Hemoglobin is the substance in red blood cells that carries oxygen to the cells. Hemoglobin reacts with blood glucose in various ways; the HbA1c sub-type reacts irreversibly. Since blood cells live about 90 days or so, the amount of HbA1c present at any time is a record of how much glucose has been in the blood during that period.
The British National Formulary (BNF) is a United Kingdom (UK) pharmaceutical reference book that contains a wide spectrum of information and advice on prescribing and pharmacology, along with specific facts and details about many medicines available on the UK National Health Service (NHS).
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Measurement of HbA1c—the predominant form of glycated hemoglobin—enables medium-term blood sugar control to be monitored in diabetes. Some glycation products are implicated in many age-related chronic diseases, including cardiovascular diseases (the endothelium, fibrinogen, and collagen are damaged) and Alzheimer's disease (amyloid proteins ...
In non-diabetic people, the HbA1c level ranges from 4.0 to 5.7%. [10] Regular 6 monthly laboratory testing of HbA1c (glycated hemoglobin) provides some assurance of long-term control and allows the adjustment of the patient's routine medication dosages in such cases.
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