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The drugs include Adderall, Vyvanse and generic amphetamines, such as dextroamphetamine. The link between amphetamines and psychosis isn’t new. Amphetamines increase levels of dopamine in the brain.
Adderall and Mydayis [11] are trade names [note 2] for a combination drug containing four salts of amphetamine.The mixture is composed of equal parts racemic amphetamine and dextroamphetamine, which produces a (3:1) ratio between dextroamphetamine and levoamphetamine, the two enantiomers of amphetamine. [13]
However Adderall can cause depression if misused or taken without a prescription. ... Does Wellbutrin give you energy? Wellbutrin works to increase the levels of neurotransmitters like dopamine ...
[10] [11] [12] Long-term use of certain substituted amphetamines, particularly methamphetamine, can reduce dopamine activity in the brain. [13] [4] Adderall- Prescribed Amphetamine. For amphetamine dependent individuals, psychotherapy is currently the best treatment option as no pharmacological treatment has been approved. [8]
Plus, there’s the question of addiction: If you stop taking stimulant medications (like Adderall) quickly after a period of chronic misuse or overuse, you may experience withdrawal symptoms.
In rodents and primates, sufficiently high doses of amphetamine cause dopaminergic neurotoxicity, or damage to dopamine neurons, which is characterized by dopamine terminal degeneration and reduced transporter and receptor function. [169] [170] There is no evidence that amphetamine is directly neurotoxic in humans.
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However, time to peak levels was delayed from 2.5 hours (range 1.5–6 hours) to 4.5 hours (range 2.5–8.0 hours). [3] During oral selegiline therapy at a dosage of 10 mg/day, circulating levels of levoamphetamine have been found to be 6 to 8 ng/mL and levels of levomethamphetamine have been reported to be 9 to 14 ng/mL. [7]
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