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Targeted temperature management (TTM), previously known as therapeutic hypothermia or protective hypothermia, is an active treatment that tries to achieve and maintain a specific body temperature in a person for a specific duration of time in an effort to improve health outcomes during recovery after a period of stopped blood flow to the brain. [1]
A study conducted in 2002-2004 showed that treatment with therapeutic hypothermia for patients resuscitated after cardiac arrest due to ventricular fibrillation led to a positive outcome (Glasgow-Pittsburgh Cerebral Performance category 1 or 2) in 24 of 43 patients compared to only 11 of 43 patients in the standard resuscitation group where no ...
A fluid warmer is a medical device used in healthcare facilities for warming fluids, crystalloid, colloid, or blood products, before being administered (intravenously or by other parenteral routes) to body temperature levels to prevent hypothermia in physically traumatized or surgical patients.
While moderate hypothermia may be satisfactory for short surgeries, deep hypothermia (20 °C to 25 °C) affords protection for times of 30 to 40 minutes at the bottom of this temperature range. Profound hypothermia (< 14 °C) usually isn't used clinically. It is a subject of research in animals and human clinical trials.
Hypothermia is a low core body temperature, defined clinically as a temperature of less than 35 degrees Celsius (95 degrees Fahrenheit). The patient is re-warmed either by using a cardiac bypass or by irrigation of the body cavities (such as thorax, peritoneum, bladder) with warm fluids; or warmed IV fluids.
Hypothermia appears to have multiple effects at a cellular level following cerebral injury. Hypothermia reduces vasogenic oedema, haemorrhage and neutrophil infiltration after trauma. [31] The release of excitatory neurotransmitters is reduced, limiting intracellular calcium accumulation.
Rewarming is typically continued until a person's temperature is greater than 32 °C (90 °F). [2] If there is no improvement at this point or the blood potassium level is greater than 12 millimoles per litre at any time, resuscitation may be discontinued. [2] Hypothermia is the cause of at least 1,500 deaths a year in the United States. [2]
Afterdrop is a continued cooling of core temperature during the initial stages of rewarming from hypothermia.. Afterdrop is attributed to the return of cold blood from extremities to the core due to peripheral vasodilatation, thus causing a further decrease of deep body temperature. [1]