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Chronic lymphocytic leukemia. Chronic lymphocytic leukemia ( CLL) is a type of cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell ). [ 2][ 8] Early on, there are typically no symptoms. [ 2] Later, non-painful lymph node swelling, feeling tired, fever, night sweats, or weight loss for no clear reason may occur ...
In combination with basic clinical symptoms, it gives in differential diagnosis the sensitivity 83.5% and specificity 77%. [16] The TK canine cancer panel is an indicator of general neoplastic disease. [17] The stage of the disease is important to treatment and prognosis. Certain blood tests have also been shown to be prognostic.
Superior vena cava syndrome ( SVCS ), is a group of symptoms caused by obstruction of the superior vena cava ("SVC"), a short, wide vessel carrying circulating blood into the heart. The majority of cases are caused by malignant tumors within the mediastinum, most commonly lung cancer and non-Hodgkin's lymphoma, directly compressing or invading ...
Mast cell activation syndrome (MCAS) is a term referring to one of two types of mast cell activation disorder (MCAD); the other type is idiopathic MCAD. [1] MCAS is an immunological condition in which mast cells inappropriately and excessively release chemical mediators, resulting in a range of chronic symptoms, sometimes including anaphylaxis or near-anaphylaxis attacks.
Specialty. Oncology. Light chain deposition disease ( LCDD) is a rare blood cell disease which is characterized by deposition of fragments of infection-fighting immunoglobulins, called light chains (LCs), in the body. LCs are normally cleared by the kidneys, but in LCDD, these light chain deposits damage organs and cause disease.
Primary central nervous system lymphoma ( PCNSL ), also termed primary diffuse large B-cell lymphoma of the central nervous system (DLBCL-CNS), [ 2] is a primary intracranial tumor appearing mostly in patients with severe immunodeficiency (typically patients with AIDS ). It is a subtype and one of the most aggressive of the diffuse large B-cell ...
Chronic myelomonocytic leukemia ( CMML) is a type of leukemia, which are cancers of the blood-forming cells of the bone marrow. In adults, blood cells are formed in the bone marrow, by a process that is known as haematopoiesis. In CMML, there are increased numbers of monocytes and immature blood cells ( blasts) in the peripheral blood and bone ...
HLH as defined by the HLH-04 criteria (see below) is a descriptive diagnosis. Its individual components are non-specific. The onset of HLH occurs before the age of one year in approximately 70 percent of cases. Familial HLH should be suspected if siblings are diagnosed with HLH or if symptoms recur when therapy has been stopped. Familial HLH is an autosomal recessive disease, hence each ...