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Large granular lymphocytic (LGL) leukemia is a chronic lymphoproliferative disorder that exhibits an unexplained, chronic (> 6 months) elevation in large granular lymphocytes (LGLs) in the peripheral blood. [1] It is divided in two main categories: T-cell LGL leukemia (T-LGLL) and natural-killer (NK)-cell LGL leukemia (NK-LGLL).
Chronic lymphocytic leukemia. Chronic lymphocytic leukemia ( CLL) is a type of cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell ). [ 2][ 8] Early on, there are typically no symptoms. [ 2] Later, non-painful lymph node swelling, feeling tired, fever, night sweats, or weight loss for no clear reason may occur ...
A complete blood count ( CBC ), also known as a full blood count ( FBC ), is a set of medical laboratory tests that provide information about the cells in a person's blood. The CBC indicates the counts of white blood cells, red blood cells and platelets, the concentration of hemoglobin, and the hematocrit (the volume percentage of red blood ...
Leukemia ( also spelled leukaemia; pronounced / luːˈkiːmiːə / [1] loo-KEE-mee-ə) is a group of blood cancers that usually begin in the bone marrow and produce high numbers of abnormal blood cells. [9] These blood cells are not fully developed and are called blasts or leukemia cells. [2]
T-cell acute lymphoblastic leukemia (T-ALL) is a type of acute lymphoblastic leukemia characterized by an aggressive malignant neoplasm of the bone marrow. [6] Acute lymphoblastic leukemia (ALL) is a condition where immature white blood cells accumulate in the bone marrow, subsequently crowding out normal white blood cells [7] and creating a build-up in the liver, spleen, and lymph nodes.
Acute myeloid leukemia ( AML) is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cell production. [ 1 ] Symptoms may include feeling tired, shortness of breath, easy bruising and bleeding, and increased risk of infection ...
Monoclonal B-cell lymphocytosis. Monoclonal B-cell lymphocytosis (MBL) is an asymptomatic condition in which individuals have increased blood levels of particular subtypes of monoclonal lymphocytes (i.e. an aberrant and potentially malignant group of lymphocytes produced by a single ancestral cell). This increase must persist for at least 3 ...
Chronic myelogenous leukemia ( CML ), also known as chronic myeloid leukemia, is a cancer of the white blood cells. It is a form of leukemia characterized by the increased and unregulated growth of myeloid cells in the bone marrow and the accumulation of these cells in the blood. CML is a clonal bone marrow stem cell disorder in which a ...