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  2. Clostridioides difficile infection - Wikipedia

    en.wikipedia.org/wiki/Clostridioides_difficile...

    Signs and symptoms of CDI range from mild diarrhea to severe life-threatening inflammation of the colon. [16]In adults, a clinical prediction rule found the best signs to be significant diarrhea ("new onset of more than three partially formed or watery stools per 24-hour period"), recent antibiotic exposure, abdominal pain, fever (up to 40.5 °C or 105 °F), and a distinctive foul odor to the ...

  3. Clostridioides difficile - Wikipedia

    en.wikipedia.org/wiki/Clostridioides_difficile

    Clostridioides difficile (syn. Clostridium difficile) is a bacterium known for causing serious diarrheal infections, and may also cause colon cancer. [4] [5] It is known also as C. difficile, or C. diff (/ s iː d ɪ f /), and is a Gram-positive species of spore-forming bacteria. [6]

  4. Antibiotic-associated diarrhea - Wikipedia

    en.wikipedia.org/wiki/Antibiotic-associated_diarrhea

    Clostridioides difficile, also known more commonly as C. diff, accounts for 10 to 20% of antibiotic-associated diarrhea cases, because the antibiotics administered for the treatment of certain disease processes such as inflammatory colitis also inadvertently kill a large portion of the gut flora, the normal flora that is usually present within the bowel.

  5. Fecal microbiota transplant - Wikipedia

    en.wikipedia.org/wiki/Fecal_microbiota_transplant

    After FMT, 20 patients were considered "cured" and a further 9 patients had a reduction in symptoms. [56] Stool transplants are considered about 90 percent effective in those with severe cases of C. difficile colonization, in whom antibiotics have not worked. [12]

  6. Bacteriotherapy - Wikipedia

    en.wikipedia.org/wiki/Bacteriotherapy

    The FDA considers fecal matter transplant a suitable treatment for select patients with C. difficile, [1] specifically when standard treatment has failed. [3] It shows a 90% success rate in clinical trials for recurrent C. difficile infections. For other illness, it is considered an experimental treatment and should only be done within a ...

  7. Vancomycin - Wikipedia

    en.wikipedia.org/wiki/Vancomycin

    treatment of infections in individuals with serious allergy to penicillins, treatment of pseudomembranous colitis caused by C. difficile; in particular, in cases of relapse or where the infection is unresponsive to metronidazole treatment (for this indication, vancomycin is given orally rather than intravenously),

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