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MDMA is a substituted amphetamine structurally, and a monoamine-releasing agent mechanistically. Like other monoamine-releasing agents, MDMA enters monoaminergic neurons through monoamine transporters. MDMA has high affinity for dopamine, norepinephrine and serotonin transporters, with some preference for the latter.
But the FDA quashed advocates’ dreams on Aug. 9, saying MDMA cannot be approved based on the data currently available and requesting additional research to prove the drug is safe and effective ...
Possible effects of using MDMA include depression, anxiety, and paranoia, while overdose effects include heart and liver failure and death, per the DEA. Read the original article on Business Insider.
[21] [22] [23] There currently is a bill pending in the California State Legislature that would legalize the "possession, obtaining, giving away, or transportation of, specified quantities of psilocybin, psilocyn, dimethyltryptamine (DMT), ibogaine, mescaline, lysergic acid diethylamide (LSD), and 3,4-methylenedioxymethamphetamine (MDMA)."
In 2024, the FDA will decide whether or not MDMA can be used to treat patients suffering from PTSD. Skip to main content. 24/7 Help. For premium support please call: 800-290-4726 ...
A 2019 double-blind study administered both MDA and MDMA to healthy volunteers. The study found that MDA shared many properties with MDMA including entactogenic and stimulant effects, but generally lasted longer and produced greater increases in psychedelic-like effects like complex imagery, synesthesia , and spiritual experiences .
Chemically, MDMA is classified as a substituted amphetamine (which includes stimulants like dextroamphetamine and psychedelics like 2,5-dimethoxy-4-methylamphetamine), which makes MDMA a substituted phenethylamine (which includes other stimulants like methylphenidate and other psychedelics like mescaline) by the definition of amphetamine.
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