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Benign prostatic hyperplasia (BPH), also called prostate enlargement, is a noncancerous increase in size of the prostate gland. [1] Symptoms may include frequent urination , trouble starting to urinate, weak stream, inability to urinate , or loss of bladder control . [ 1 ]
Around one third of men will develop urinary tract (outflow) symptoms, of which the principal underlying cause is benign prostatic hyperplasia. [26] Once symptoms arise, their progress is variable and unpredictable with about one third of patients improving, one third remaining stable and one third deteriorating. [citation needed]
The International Prostate Symptom Score (IPSS) is an eight-question written screening tool used to screen for, rapidly diagnose, track the symptoms of, and suggest management of the lower urinary tract symptoms of benign prostatic hyperplasia (BPH).
Benign Prostatic Hyperplasia symptoms. National Health Service. Early Detection of Prostate Cancer: AUA/SOU Guideline Part 1: Prostate Cancer Screening. The Journal of Urology. 2023.
Some of the more commonly known clinical forms of hyperplasia, or conditions leading to hyperplasia, include: Benign prostatic hyperplasia, also known as prostate enlargement. [1] Cushing's disease – Physiopathology of hyperplasia of adrenal cortex due to increased circulating level of ACTH (adrenocorticotropic hormone). [18]
Saw palmetto, a phytotherapeutic agent, has been shown to reduce prostatic congestion and urinary symptoms related to benign prostate hyperplasia. The exact mechanism is unknown however it is commonly believed to work by inhibiting the enzyme 5-alpha reductase that converts testosterone into dihydrotestosterone, its active metabolite. [23]
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