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Diffuse injury has more microscopic injury than macroscopic injury and is difficult to detect with CT and MRI, but its presence can be inferred when small bleeds are visible in the corpus callosum or the cerebral cortex. [34] MRI is more useful than CT for detecting characteristics of diffuse axonal injury in the subacute and chronic time ...
Such microhemorrhages are difficult to be detected on CT scan, but easily detected on gradient echo and susceptibility weighted imaging on MRI scan as hypointense susceptibility blooming. Such microhemorrhages are frequently associated with diffuse axonal injury and located near the grey-white matter junction. [3]
Rotational forces are a common cause of diffuse injuries; [5] these forces are common in diffuse injuries such as concussion and diffuse axonal injury. The term "diffuse" has been called a misnomer, since injury is often actually multifocal, with multiple locations of injury. [2] Diffuse injuries include the following: Diffuse axonal injury is ...
Comparison of diffuse axonal injury imaged with conventional GRE (left) and SWI (right) at 1.5 T Comparison of hemorrhage imaged with conventional GRE (left) and SWI (right) at 1.5 T The detection of micro-hemorrhages, shearing, and diffuse axonal injury (DAI) in trauma patients is often difficult as the injuries tend to be relatively small in ...
Diffuse axonal injury is caused by shearing forces on the brain leading to lesions in the white matter tracts of the brain. [31] These shearing forces are seen in cases where the brain had a sharp rotational acceleration, and is caused by the difference in density between white matter and grey matter. [32]
Closed head injury (coup contrecoup) can damage more than the impact sites on the brain, as axon bundles may be torn or twisted, blood vessels may rupture, and elevated intracranial pressure can distort the walls of the ventricles. [7] [10] [11] Diffuse axonal injury is a key pathology in concussive brain injury. [5] The visual system may be ...
Computed tomography (CT) has become the diagnostic modality of choice for head trauma due to its accuracy, reliability, safety, and wide availability. The changes in microcirculation, impaired auto-regulation, cerebral edema, and axonal injury start as soon as a head injury occurs and manifest as clinical, biochemical, and radiological changes ...
T 2 *-weighted sequences are used to detect deoxygenated hemoglobin, methemoglobin, or hemosiderin in lesions and tissues. [2] Diseases with such patterns include intracranial hemorrhage, arteriovenous malformation, cavernoma, hemorrhage in a tumor, punctate hemorrhages in diffuse axonal injury, superficial siderosis, thrombosed aneurysm, phleboliths in vascular lesions, and some forms of ...