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Opioids such as neonatal morphine solution and methadone are commonly used to treat clinical symptoms of opiate withdrawal, but may prolong neonatal drug exposure and duration of hospitalization. [42] A study demonstrated a shorter wean duration in infants treated with methadone compared to those treated with diluted tincture of opium. When ...
Opioids can cross both the placental and blood-brain barriers, which poses risks to fetuses and newborns exposed to these drugs before birth. This exposure to opioids during pregnancy can lead to potential obstetric complications, including spontaneous abortion, abruption of the placenta, pre-eclampsia, prelabor rupture of membranes, and fetal death.
Buprenorphine/naloxone, sold under the brand name Suboxone among others, is a fixed-dose combination medication that includes buprenorphine and naloxone. [3] It is used to treat opioid use disorder, and reduces the mortality of opioid use disorder by 50% (by reducing the risk of overdose on full-agonist opioids such as heroin or fentanyl).
Like methadone, Suboxone blocks both the effects of heroin withdrawal and an addict’s craving and, if used properly, does it without causing intoxication. Unlike methadone, it can be prescribed by a certified family physician and taken at home, meaning a recovering addict can lead a normal life, without a daily early-morning commute to a clinic.
Buprenorphine, sold under the brand name Subutex among others, is an opioid used to treat opioid use disorder, acute pain, and chronic pain. [18] It can be used under the tongue (sublingual), in the cheek (buccal), by injection (intravenous and subcutaneous), as a skin patch (transdermal), or as an implant.
Compared to methadone, it consistently results in improved birth weight and gestational age, though these findings should be interpreted with caution due to potential biases. [156] Buprenorphine use also correlates with a lower risk of adverse neonatal outcomes, with similar risks of adverse maternal outcomes as methadone. [157]
The journal was originally established as The Journal of Maternal-Fetal Medicine in 1992, under Wiley-Liss. A separate journal, Prenatal and Neonatal Medicine was established in 1996, published by the Parthenon Publishing Group. In 2002, both journal merged together to form the Journal of Maternal-Fetal and Neonatal Medicine.
"After-Birth Abortion: Why Should the Baby Live?" [1] is a controversial article published by Francesca Minerva and Alberto Giubilini. Available online from 2012 and published in the Journal of Medical Ethics in 2013, [ 2 ] it argues to call child euthanasia or infanticide "after-birth abortion" and highlights similarities between abortion and ...