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[1] [2] [3] It is either taken by mouth or applied to the skin as a cream or ointment. [1] [4] The cream and ointment should not be used for fungal nail infections. [5] Common side effects when taken by mouth include nausea, diarrhea, headache, cough, rash, and elevated liver enzymes. [1] Severe side effects include liver problems and allergic ...
The strength of topical hydrocortisone products ranges from 0.1% to 2.5%, which means there could be 1 mg to 25 mg hydrocortisone in 1g of the products. [12] Some formulations for topical hydrocortisone include hydrocortisone 0.5% cream or ointment, hydrocortisone 1% cream or ointment, and hydrocortisone 2.5% cream or ointment. [34]
Triamcinolone acetonide, also known as 9α-fluoro-16α-hydroxyprednisolone 16α,17α-acetonide or as 9α-fluoro-11β,16α-17α,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone, is a synthetic halogenated cyclic ketal pregnane corticosteroid. [27] It is the C16α,17α acetonide of triamcinolone. [27]
Side effects may occur from sudden discontinuation and prolonged, continuous use can lead to skin thinning. [2] Intermittent use of topical steroids for atopic dermatitis is safe and does not cause skin thinning.
Side effects of triamcinolone long-term treatment may include coughing (up to bronchospasms), sinusitis, metabolic syndrome–like symptoms such as high blood sugar and cholesterol, weight gain due to water retention, and electrolyte imbalance, as well as cataract, thrush, osteoporosis, reduced muscle mass, and psychosis.
In general, use a potent preparation short term and weaker preparation for maintenance between flare-ups. While there is no proven best benefit-to-risk ratio, [11] if prolonged use of a topical steroid on a skin surface is required, a pulse therapy should be undertaken.
Side effects of desonide requiring immediate contact with the prescribing physician: Blistering, burning, crusting, dryness, or flaking of the skin; burning, itching, redness, skin rash, swelling, or soreness at the application site; flushing or redness of the skin; irritation; itching, scaling, severe redness, soreness, or swelling of the skin
[1] Prevention of atopic dermatitis is typically with essential fatty acids, [4] and may be treated with moisturizers and steroid creams. [5] The steroid creams should generally be of mid-to high strength and used for less than two weeks at a time, as side effects can occur. [8] Antibiotics may be required if there are signs of skin infection. [2]
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