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Cocaine dependence is a neurological disorder that is characterized by withdrawal symptoms upon cessation from cocaine use. [1] It also often coincides with cocaine addiction which is a biopsychosocial disorder characterized by persistent use of cocaine and/or crack despite substantial harm and adverse consequences.
Coca leaves have been used by Andean civilizations since ancient times. [30] In ancient Wari culture, [33] Inca culture, and through modern successor indigenous cultures of the Andes mountains, coca leaves are chewed, taken orally in the form of a tea, or alternatively, prepared in a sachet wrapped around alkaline burnt ashes, and held in the mouth against the inner cheek; it has traditionally ...
Substance dependence, also known as drug dependence, is a biopsychological situation whereby an individual's functionality is dependent on the necessitated re-consumption of a psychoactive substance because of an adaptive state that has developed within the individual from psychoactive substance consumption that results in the experience of withdrawal and that necessitates the re-consumption ...
A large protein molecule attaches to cocaine, which stimulates response from antibodies, which destroy the molecule. This also prevents the cocaine from crossing the blood–brain barrier, negating the euphoric high and rewarding effect of cocaine caused from stimulation of dopamine release in the mesolimbic reward pathway. The vaccine does not ...
The etymology of the term addiction throughout history has been misunderstood and has taken on various meanings associated with the word. [195] An example is the usage of the word in the religious landscape of early modern Europe. [196] "Addiction" at the time meant "to attach" to something, giving it both positive and negative connotations.
This is a list of states (and some territories) by the annual prevalence of cocaine use as percentage of the population aged 15–64 (unless otherwise indicated). [1] published by the United Nations Office on Drugs and Crime (UNODC). The indicator is the "annual prevalence" rate which is the percentage of the youth and adult population who have ...
Number with a drug use disorders by substance, OWID. Substance-related disorders, also known as substance use disorders, can lead to large societal problems.It is found to be greatest in individuals ages 18–25, with a higher likelihood occurring in men compared to women, and urban residents compared to rural residents.
Cocaine increases alertness, feelings of well-being, euphoria, energy, sociability, and sexuality. The former are some of the desired effects of cocaine intoxication. Not having the normal use of mental faculties by reason of the introduction of cocaine is defined drug intoxication by the laws in America, Europe, and most of the rest of the World, and it is a serious crime in specific contexts ...
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