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  2. Post-exertional malaise - Wikipedia

    en.wikipedia.org/wiki/Post-exertional_malaise

    It is the hallmark symptom of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and common in long COVID and fibromyalgia. [3] [1] PEM is often severe enough to be disabling, and is triggered by ordinary activities that healthy people tolerate. Typically, it begins 12–48 hours after the activity that triggers it, and lasts for days ...

  3. Excessive daytime sleepiness - Wikipedia

    en.wikipedia.org/wiki/Excessive_daytime_sleepiness

    Treatment of excessive daytime sleepiness (EDS) relies on identifying and treating the underlying disorder which may cure the person from the EDS. Drugs like modafinil , [ 22 ] armodafinil , [ 23 ] pitolisant [ 24 ] (Wakix), sodium oxybate (Xyrem) oral solution, have been approved as treatment for EDS symptoms in the United States.

  4. Central nervous system fatigue - Wikipedia

    en.wikipedia.org/wiki/Central_Nervous_System_Fatigue

    Central nervous system fatigue, or central fatigue, is a form of fatigue that is associated with changes in the synaptic concentration of neurotransmitters within the central nervous system (CNS; including the brain and spinal cord) which affects exercise performance and muscle function and cannot be explained by peripheral factors that affect muscle function.

  5. Lethargy - Wikipedia

    en.wikipedia.org/wiki/Lethargy

    Lethargy is a state of tiredness, sleepiness, weariness, fatigue, sluggishness, or lack of energy. It can be accompanied by depression , decreased motivation, or apathy . Lethargy can be a normal response to inadequate sleep, overexertion, overworking, stress, lack of exercise, improper nutrition, drug abuse, boredom , or a symptom of an ...

  6. Short sleep negates benefits of exercise for the brain, study ...

    www.aol.com/news/short-sleep-negates-benefits...

    Using alcohol to sleep will cause you to wake up within a few hours and when you sleep again, it’s typically poor quality. One of the most important things to do, experts say, is make a sleep ...

  7. Clinical descriptions of ME/CFS - Wikipedia

    en.wikipedia.org/wiki/Clinical_descriptions_of...

    The fatigue must have lasted for 6 months or longer, and be present at least 50% of the time; Other symptoms are possible, such as muscle pain, mood problems, or sleep disturbance; Conditions known to cause severe fatigue and some mental conditions exclude a diagnosis. Post-infectious fatigue syndrome also requires evidence of a prior infection ...

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