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Tabernaemontana divaricata. Conolidine is an indole alkaloid.Preliminary reports suggest that it could provide analgesic effects with few of the detrimental side-effects associated with opioids such as morphine, though at present it has only been evaluated in mouse models.
A syrette is a single-use device for injecting liquid through a needle. It is similar to a syringe except that it has a sealed squeeze tube instead of a rigid tube and piston . It was developed by the pharmaceutical manufacturer E.R. Squibb & Sons (eventually merged into the current day Bristol-Myers Squibb ) just prior to World War II (WWII).
Paregoric was used in various formulations for hundreds of years. [citation needed] Paregoric was a household remedy in the 18th and 19th centuries when it was widely used to control diarrhea in adults and children, as an expectorant and cough medicine, to calm fretful children, and to rub on the gums to counteract the pain from teething.
Federal authorities say a Minnesota pharmacist took morphine from the “stock bottle” meant to fulfill patient prescriptions and replaced the missing liquid with water.. In doing so, the 42 ...
Laudanum was historically used to treat a variety of conditions, but its principal use was as a pain medication and cough suppressant. Until the early 20th century, laudanum was sold without a prescription and was a constituent of many patent medicines .
It is mainly used as an analgesic (pain medication). There are numerous methods used to administer morphine: orally; administered under the tongue; via inhalation; injection into a vein, injection into a muscle, injection under the skin, or injection into the spinal cord area; transdermal; or via administered into the rectal canal suppository.
Hydromorphone, also known as dihydromorphinone, and sold under the brand name Dilaudid among others, is a morphinan opioid used to treat moderate to severe pain. [7] Typically, long-term use is only recommended for pain due to cancer. [9] It may be used by mouth or by injection into a vein, muscle, or under the skin. [7]
Carbonate derivatives of 14β-hydroxycodeine "viz., 14β-hydroxy-6-O-(methoxycarbonyl)codeine, 6-O-methoxycarbonyl-14β-(methoxycarbonyloxy)codeine, and 14β-acetoxy-6-O-methoxy-carbonylcodeine, potential substrates for ring C modification in morphinane (sic) alkaloids, were synthesized for the first time."