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Patient A was a 33-year old female diagnosed with primary erythromelalgia at age 30 and suffered from burning and pain in her feet since she was 8 years old (Wu et. al 2013). Patient B was a 16 year-old girl with recurrent severe burning pain of both feet since the age of seven (Wu et. al 2013).
Pain or burning along the length of the vein; Vein being hard and cord-like [2] There is usually a slow onset of a tender red area along the superficial veins on the skin. A long, thin red area may be seen as the inflammation follows a superficial vein. This area may feel hard, warm, and tender. The skin around the vein may be itchy and swollen.
Chronic venous insufficiency (CVI) is a medical condition characterized by blood pooling in the veins, leading to increased pressure and strain on the vein walls. [1] The most common cause of CVI is superficial venous reflux, which often results in the formation of varicose veins, a treatable condition. [2]
Because of its similarities to deep vein thrombosis (DVT), May–Thurner syndrome is rarely diagnosed amongst the general population. In this condition, the right iliac artery sequesters and compresses the left common iliac vein against the lumbar section of the spine, [5] resulting in swelling of the legs and ankles, pain, tingling, and/or numbness in the legs and feet. [6]
Early treatment options include medroxyprogesterone or nonsteroidal anti-inflammatory drugs (NSAIDs). [1] Surgery to block the varicose veins may also be done. [1] About 30% of women of reproductive age are affected. [6] It is believed to be the cause of about a third of chronic pelvic pain cases. [5]
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DVT usually occurs in the veins of the legs, although it can also occur in the veins of the arms. Immobility, active cancer, obesity, traumatic damage and congenital disorders that make clots more likely are all risk factors for deep vein thrombosis. It can cause the affected limb to swell, and cause pain and an overlying skin rash.
Here you can see a typical test where the first lactate threshold is at around 210-215 power output and their second lactate threshold is at 260-265.
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