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The combination of an inappropriate rapid heart rate response to exercise with heavy or rapid breathing is known as an exaggerated cardiorespiratory response to exercise. [3] Due to the confusion between muscle fatigue and muscle weakness, there have been instances of abnormal muscle fatigue being described as exercise-induced muscle weakness.
The CPET test measures exercise capacity and help determine whether the cause of exercise intolerance is due to heart disease or to other causes. [3] People who experience significant fatigue before reaching the anaerobic threshold usually have a non-cardiac cause for exercise intolerance. [3]
Fatigue in a medical context is used to cover experiences of low energy that are not caused by normal life. [2] [3]A 2021 review proposed a definition for fatigue as a starting point for discussion: "A multi-dimensional phenomenon in which the biophysiological, cognitive, motivational and emotional state of the body is affected resulting in significant impairment of the individual's ability to ...
Iron deficiency anemia can intensify symptoms of fatigue and shortening of breath, and can cause cold sensitivity, hair loss, paleness to the skin and nail changes, says Cunningham. It has also ...
According to the World Health Organization, nearly 1 in 6 people worldwide are living with a neurological disorder. In the U.S. alone, approximately 5.8 million people have Alzheimer's disease ...
In the brain, serotonin is a neurotransmitter and regulates arousal, behavior, sleep, and mood, among other things. [9] During prolonged exercise where central nervous system fatigue is present, serotonin levels in the brain are higher than normal physiological conditions; these higher levels can increase perceptions of effort and peripheral muscle fatigue. [9]
Post-exertional malaise (PEM), sometimes referred to as post-exertional symptom exacerbation (PESE) [1] or post-exertional neuroimmune exhaustion (PENE), [2] is a worsening of symptoms that occurs after minimal exertion.
Endorphins are credited as the cause of the feeling of euphoria and wellbeing found in many forms of exercise, so proponents of this theory believe that the second wind is caused by their early release. [13] Many of these proponents feel that the second wind is very closely related to—or even interchangeable with—the runner's high. [14]