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In people with Barrett’s esophagus who are affected by reflux symptoms, the symptoms may be triggered by certain foods, especially spicy, citric or hot foods, as well as other stimuli, such as alcohol and coffee.
Most EAC cases arise in the setting of a detectable preneoplastic lesion known as Barrett's esophagus (BE). It has become well established that gastroesophageal reflux disease (GERD) is a common and strong risk factor (i.e., with a large attributable fraction) for both BE and EAC.
We assessed the risk of Barrett’s esophagus associated with total and beverage-specific alcohol consumption by pooling individual participant data from five case-control studies participating in the international Barrett’s and Esophageal Adenocarcinoma Consortium (BEACON).
alcohol drinking has long been strongly and consistently linked with increased risk of esophageal squamous can- cer, its role in BE and EAC is less well studied.
Total alcohol consumption at age 21 years was significantly associated with reflux esophagitis (OR, 2.24, 1.35–3.74) but not with Barrett's esophagus or esophageal adenocarcinoma (OR, 1.06, 0.63–1.79 and OR, 1.27, 0.77–2.10, respectively).
Most EAC cases arise in the setting of a detectable preneoplastic lesion known as Barrett's esophagus (BE). It has become well-established that gastroesophageal reflux disease (GERD) is a common and strong risk factor (ie, with a large attributable fraction) for both BE and EAC.
Objectives: Alcohol is a carcinogen that may increase the risk of Barrett's esophagus (BE) through direct contact with esophageal mucosa. However, few studies have investigated this association and findings have been inconsistent.
The association between alcohol consumption and Barrett's esophagus (BE) remained uncertain and controversial in the previous studies. We performed a meta-analysis of observational studies to clarify the association.
Several studies have been proposed to investigate the association between alcohol consumption and risk of Barrett’s esophagus (BE), but as of yet, no quantitative summary of the literature...
We assessed the risk of Barrett's esophagus associated with total and beverage-specific alcohol consumption by pooling individual participant data from five case-control studies participating in the international Barrett's and Esophageal Adenocarcinoma Consortium.