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Erectile dysfunction (ED), also referred to as impotence, is a form of sexual dysfunction in males characterized by the persistent or recurring inability to achieve or maintain a penile erection with sufficient rigidity and duration for satisfactory sexual activity.
Here’s a fun fact, actually: According to Johnson, the main active ingredients of erectile dysfunction medications Cialis and Viagra—tadalafil and sildenafil—work by lowering blood pressure.
Although erections are not necessary for satisfying sexual encounters, many men see them as important, and treating erectile dysfunction improves their relationships and quality of life. [78] Whatever treatment is used, it works best in combination with talk-oriented therapy to help integrate it into the sex life. [ 65 ]
According to the study, "'overall treatment outcomes were poor, with low satisfaction rates and significant risk of major complications, including penile deformity, shortening, and erectile dysfunction'". [15] Medical doctors do treat micropenis with surgical procedures. [6] In such cases, surgery can improve urinary or sexual function. [17]
Low-intensity extracorporeal shock wave therapy has been used as a treatment for erectile dysfunction. [23] It differs from palliative options by aiming to restore natural erectile function by inducing cellular microtrauma, triggering the release of angiogenic factors and promoting neovascularization in treated tissue. This mechanism is ...
Men who reported severe erectile dysfunction—difficulty getting and keeping an erection—improved 4.9 points on a scale of 6-30, with higher scores indicating better function.
Trimix is a combination of three drugs: alprostadil, papaverine, and phentolamine. These medications work in combination to increase blood flow to the penis, resulting in an erection. [1] [2] [3] Alprostadil is a prostaglandin vasodilator that allows more blood to flow into the area by relaxing the smooth muscle in the blood vessels of the penis.
Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.
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