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Bicalutamide may cause sexual dysfunction, including decreased sex drive and erectile dysfunction. [8] However, the rates of these side effects with bicalutamide monotherapy are very low. [ 8 ] In the EPC trial, at 7.4 years follow-up, the rates of decreased libido and impotence were only 3.6% and 9.3% in the 150 mg/day bicalutamide monotherapy ...
Focused shockwave therapy appears to work best for males with vasculogenic ED, which is a blood vessel disorder that affects blood flow to tissue in the penis. The treatment is painless and has no known side effects. Treatment with shockwave therapy can lead to a significant improvement of the IIEF (International Index of Erectile Function).
Here’s a fun fact, actually: According to Johnson, the main active ingredients of erectile dysfunction medications Cialis and Viagra—tadalafil and sildenafil—work by lowering blood pressure.
Trimix is a combination of three drugs: alprostadil, papaverine, and phentolamine. These medications work in combination to increase blood flow to the penis, resulting in an erection. [1] [2] [3] Alprostadil is a prostaglandin vasodilator that allows more blood to flow into the area by relaxing the smooth muscle in the blood vessels of the penis.
Side effects include decreased breathing or a lack of breathing at high doses. The medication can also cause hypotension, or low blood pressure. [4] Alprostadil is also used for adults with erectile dysfunction. It is typically given when other medications are ineffective.
Low-intensity extracorporeal shock wave therapy has been used as a treatment for erectile dysfunction. [23] It differs from palliative options by aiming to restore natural erectile function by inducing cellular microtrauma, triggering the release of angiogenic factors and promoting neovascularization in treated tissue. This mechanism is ...
Gabapentin is also associated with other intimate side effects, like difficulty reaching orgasm, although the science on this link isn’t totally clear. ED from gabapentin isn’t permanent.
Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.
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