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  2. Drug tolerance - Wikipedia

    en.wikipedia.org/wiki/Drug_tolerance

    drug sensitization or reverse tolerance – the escalating effect of a drug resulting from repeated administration at a given dose; drug withdrawal – symptoms that occur upon cessation of repeated drug use; physical dependencedependence that involves persistent physical–somatic withdrawal symptoms (e.g., fatigue and delirium tremens)

  3. Addiction - Wikipedia

    en.wikipedia.org/wiki/Addiction

    drug sensitization or reverse tolerance – the escalating effect of a drug resulting from repeated administration at a given dose; drug withdrawal – symptoms that occur upon cessation of repeated drug use; physical dependencedependence that involves persistent physical–somatic withdrawal symptoms (e.g., fatigue and delirium tremens)

  4. Substance abuse - Wikipedia

    en.wikipedia.org/wiki/Substance_abuse

    The Health Officers Council of British Columbia — in their 2005 policy discussion paper, A Public Health Approach to Drug Control in Canada — has adopted a public health model of psychoactive substance use that challenges the simplistic black-and-white construction of the binary (or complementary) antonyms "use" vs. "abuse". [11]

  5. Substance dependence - Wikipedia

    en.wikipedia.org/wiki/Substance_dependence

    Substance dependence, also known as drug dependence, is a biopsychological situation whereby an individual's functionality is dependent on the necessitated re-consumption of a psychoactive substance because of an adaptive state that has developed within the individual from psychoactive substance consumption that results in the experience of withdrawal and that necessitates the re-consumption ...

  6. Dying To Be Free - The Huffington Post

    projects.huffingtonpost.com/dying-to-be-free...

    Chemistry, not moral failing, accounts for the brain’s unwinding. In the laboratories that study drug addiction, researchers have found that the brain becomes conditioned by the repeated dopamine rush caused by heroin. “The brain is not designed to handle it,” said Dr. Ruben Baler, a scientist with the National Institute on Drug Abuse.

  7. Addictive behavior - Wikipedia

    en.wikipedia.org/wiki/Addictive_behavior

    drug sensitization or reverse tolerance – the escalating effect of a drug resulting from repeated administration at a given dose; drug withdrawal – symptoms that occur upon cessation of repeated drug use; physical dependencedependence that involves persistent physical–somatic withdrawal symptoms (e.g., fatigue and delirium tremens)

  8. Reverse tolerance - Wikipedia

    en.wikipedia.org/wiki/Reverse_tolerance

    Reverse tolerance or drug sensitization is a pharmacological phenomenon describing subjects' increased reaction (positive or negative) to a drug following its repeated use. [4] Not all drugs are subject to reverse tolerance. This is the opposite of drug tolerance, in which the effect or the subject's reaction decreases following its repeated ...

  9. Substance use disorder - Wikipedia

    en.wikipedia.org/wiki/Substance_use_disorder

    drug sensitization or reverse tolerance – the escalating effect of a drug resulting from repeated administration at a given dose; drug withdrawal – symptoms that occur upon cessation of repeated drug use; physical dependencedependence that involves persistent physical–somatic withdrawal symptoms (e.g., fatigue and delirium tremens)