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In mice this disinfectant was found to cause infertility and birth defects when combined with Alkyl (60% C14, 25% C12, 15% C16) dimethyl benzyl ammonium chloride (ADBAC). [ 5 ] [ 6 ] These studies contradict the older toxicology data set on quaternary ammonia compounds which was reviewed by the U.S. Environmental Protection Agency (U.S. EPA ...
Coccidia can infect all mammals, some birds, some fish, some reptiles, and some amphibians. Most species of coccidia are species-specific in their host. An exception is Toxoplasma gondii, which can infect all mammals, although it can only undergo sexual reproduction in cats. Depending on the species of coccidia, infection can cause fever ...
Of the azoles, ketoconazole is the only one approved by the U.S. Food and Drug Administration (FDA) for treatment of coccidioidomycosis. Nevertheless, although it was initially used in the long-term treatment of nonmeningeal extrapulmonary disease, more-potent, less-toxic triazoles (fluconazole and itraconazole) have replaced it. Itraconazole ...
While coccidia can infect a wide variety of animals, including humans, birds, and livestock, they are usually species-specific. One well-known exception is toxoplasmosis caused by Toxoplasma gondii. [1] [2] Humans may first encounter coccidia when they acquire a dog, cat or bird that is infected.
Heat treatment can be used for disinfection and sterilization. [42] The phrase "sunlight is the best disinfectant" was popularized in 1913 by United States Supreme Court Justice Louis Brandeis [43] and later advocates of government transparency.
Chlorhexidine [1] is a disinfectant and antiseptic with the molecular formula C 22 H 30 Cl 2 N 10, which is used for skin disinfection before surgery and to disinfect surgical instruments. [2] It is also used for cleaning wounds, preventing dental plaque, treating yeast infections of the mouth, and to keep urinary catheters from blocking. [3]
Merbromin's best-known use is as a topical antiseptic to treat minor wounds, burns, and scratches. [3] It is also used in the antisepsis of the umbilical cord, [4] and the antisepsis of wounds with inhibited scar formation, such as neuropathic ulcers and diabetic foot sores. [5]
Mild asymptomatic cases often do not require any treatment. Those with severe symptoms may benefit from antifungal therapy, which requires 3–6 months or more of treatment depending on the response to the treatment. [32] There is a lack of prospective studies that examine optimal antifungal therapy for coccidioidomycosis. [citation needed]
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