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Urolithins are microflora metabolites of dietary ellagic acid derivatives, such as ellagitannins. [1] They are produced in the gut , and found in the urine in the form of urolithin B glucuronide after absorption of ellagitannins-containing foods, such as pomegranate . [ 2 ]
When synthesized and absorbed in the intestines, urolithin A enters the systemic circulation where it becomes available to tissues throughout the body where it is further subjected to additional chemical transformations (including glucuronidation, methylation, sulfation, or a combination of them) within the enterocytes and hepatocytes. [9]
When inflammation becomes long-term (or chronic), it can start damaging tissues and interfering with your body’s normal functions. ... Beyond omega-3s and urolithins, ...
Not all elements which are found in the human body in trace quantities play a role in life. Some of these elements are thought to be simple common contaminants without function (examples: caesium, titanium), while many others are thought to be active toxins, depending on amount (cadmium, mercury, lead, radioactives).
The recommended daily allowance for protein is 0.8 grams protein per kilogram of body weight, but as Groves points out, this is just a general recommendation. “This amount is necessary to ...
This hormone plays an important role in maintaining your body’s growth and metabolism by acting on various cells, tissues and organs. ... Not only is muscle necessary for normal function, having ...
Urolithins are gut flora human metabolites of dietary ellagic acid derivatives. [ 3 ] [ 4 ] Ellagic acid has low bioavailability, with 90% remaining unabsorbed from the intestines until metabolized by microflora to the more bioavailable urolithins.
Heart attacks and strokes occur when plaque forms in arteries, which can slow down blood flow in the body and cause small blood clots to form.