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Leishmaniasis is a wide array of clinical manifestations caused by protozoal parasites of the Trypanosomatida genus Leishmania. [7] It is generally spread through the bite of phlebotomine sandflies , Phlebotomus and Lutzomyia , and occurs most frequently in the tropics and sub-tropics of Africa, Asia, the Americas, and southern Europe.
Leishmania / l iː ʃ ˈ m eɪ n i ə,-ˈ m æ n-/ [1] is a parasitic protozoan, a single-celled organism of the genus Leishmania that is responsible for the disease leishmaniasis. [2] [3] [4] They are spread by sandflies of the genus Phlebotomus in the Old World, and of the genus Lutzomyia in the New World.
Cutaneous leishmaniasis is commonly characterized with skin lesions, which can appear localized, or throughout the body. While mucocutaneous leishmaniasis is characterized with ulcers around the skin, mouth, and nose. This form of Leishmaniasis has also been known to can spread by metastasis and can be deadly. [2]
Mucocutaneous leishmaniasis is an especially disturbing form of cutaneous leishmaniasis, because it produces destructive and disfiguring lesions of the face. It is most often caused by Leishmania braziliensis, but cases caused by L. aethiopica have also been described. [10] Mucocutaneous leishmaniasis is very difficult to treat.
Candida albicans infection; Candida parapsilosis infection; Cytomegalovirus infection; diphtheria; human coronavirus infection; respiratory distress syndrome; measles; meconium aspiration syndrome
Visceral leishmaniasis (VL), also known as kala-azar (Hindi: kālā āzār, "black sickness") [2] or "black fever", is the most severe form of leishmaniasis and, without proper diagnosis and treatment, is associated with high fatality. [3] Leishmaniasis is a disease caused by protozoan parasites of the genus Leishmania.
L. tropica causes a broad spectrum of leishmaniasis forms in humans. Most common is a variant called dry-type cutaneous leishmaniasis. After an incubation period lasting more than 2 months, a small brownish nodular lesion will appear with a slowly extending plaque reaching a size of 1–2 centimetres (0.39–0.79 in) after 6 months.
The parasite which causes leishmaniasis is Leishmania, which is a Trypanosomatida. The disease spreads to humans from sandflies , which act as vectors for the parasite when they bite. [ 3 ] Animals (such as dogs and rodents) can be a reservoir for the parasite, spreading it to sandflies, and from sandflies to humans.