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Splenomegaly is an enlargement of the spleen. [1] The spleen usually lies in the left upper quadrant (LUQ) of the human abdomen.Splenomegaly is one of the four cardinal signs of hypersplenism which include: some reduction in number of circulating blood cells affecting granulocytes, erythrocytes or platelets in any combination; a compensatory proliferative response in the bone marrow; and the ...
The typical size is approximately 1 centimeter, but sizes ranging from a few millimeters up to 2–3 centimeters are not uncommon. [2] Splenogonadal fusion can result in one or more accessory spleens along a path from the abdomen into the pelvis or scrotum. The developing spleen forms near the urogenital ridge from which the gonads develop. The ...
Acquired asplenia occurs for several reasons: . Following splenectomy due to splenic rupture from trauma or because of tumor; After splenectomy with the goal of interfering with splenic function, as a treatment for diseases (e.g. idiopathic thrombocytopenic purpura, thalassemia, spherocytosis), in which the spleen's usual activity exacerbates the disease
The risk is greatest for children and elderly (70+ years old), but it can happen at any age. Greater risk is associated with splenectomy for hematological conditions such as sickle cell anemia, thalassemia and tumours when compared to splenectomy due to trauma. [2] [4]
In 2003, Children's began an $80 million, 160,000-square-foot (15,000 m 2) clinical expansion and started renovating 100,000 square feet (9,300 m 2) of existing space. Children's became the first freestanding children's hospital in Ohio to receive “Magnet Recognition” in 2004, which is the highest honor for excellence in nursing. [23]
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Much of the spleen's protective roles can be maintained if a small amount of spleen can be left behind. [17] Where clinically appropriate, attempts are now often made to perform either surgical subtotal (partial) splenectomy, [ 18 ] or partial splenic embolization . [ 19 ]
Wandering spleen is most commonly diagnosed in young children [3] as well as women between the ages of 20 and 40. [6] Even so, the disease is very rare and fewer than 500 occurrences of the disease have been reported as of 2005, [3] of which around 148 (including both children and adult cases) were documented to have been from between 1960 and ...