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A particular interest in oat β-glucan arose after a cholesterol lowering effect from oat bran reported in 1981. [2] In 1997, the FDA approved of a claim that intake of at least 3.0 g of β-glucan from oats per day decreased absorption of dietary cholesterol and reduced the risk of coronary heart disease. The approved health claim was later ...
A 2021 meta-analysis of clinical trials concluded that oat beta-glucan with molecular weights greater than 300 kg/mol reduced incremental area-under-the-curve by 23%, peak blood glucose by 28%, and insulin by 22% in a dose-responsive fashion, with similar results in participants with or without diabetes. [24]
As a rich source of dietary fiber (10 grams per 100 gram serving), whole oats supply beta-glucan (4 grams per 100 gram serving; table), a soluble fiber with cholesterol-lowering effects. [ 3 ] [ 6 ] [ 7 ]
Mixed-linkage glucan (MLG), sometimes incorrectly referred to as beta-glucan, is a hemicellulosic polysaccharide consisting of β-D(1-3) and β-D(1-4) linked glucosyl residues. MLG is highly prevalent within the Poales , where it has important properties in the diet .
A glucan is a polysaccharide derived from D-glucose, [1] linked by glycosidic bonds. Glucans are noted in two forms: alpha glucans and beta glucans. Many beta-glucans are medically important. They represent a drug target for antifungal medications of the echinocandin class.
Image source: Getty Images. How Social Security calculates your monthly benefit. Social Security calculates your monthly benefit using your average earnings during the 35 years when you earned the ...
In pharmacology, the international unit (IU) is a unit of measurement for the effect or biological activity of a substance, for the purpose of easier comparison across similar forms of substances. International units are used to quantify vitamins and biologics ( hormones , some medications , vaccines , blood products and similar biologically ...
The enzyme glucan 1,4-β-glucosidase (EC 3.2.1.74), also known as 4-β-D-glucan glucohydrolase, catalyses the hydrolysis of (1→4)-linkages in 1,4-β-D-glucans and related oligosaccharides, removing successive glucose units.
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