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Coronary ischemia, myocardial ischemia, [1] or cardiac ischemia, [2] is a medical term for abnormally reduced blood flow in the coronary circulation through the coronary arteries. [3] Coronary ischemia is linked to heart disease, and heart attacks. [4] Coronary arteries deliver oxygen-rich blood to the heart muscle. [5]
Cardiac ischemia may be asymptomatic or may cause chest pain, known as angina pectoris. It occurs when the heart muscle, or myocardium , receives insufficient blood flow. [ 10 ] This most frequently results from atherosclerosis , which is the long-term accumulation of cholesterol-rich plaques in the coronary arteries .
Ischemic cardiomyopathy is a type of cardiomyopathy caused by a narrowing of the coronary arteries which supply blood to the heart. [4] Typically, patients with ischemic cardiomyopathy have a history of acute myocardial infarction, [5] however, it may occur in patients with coronary artery disease, but without a past history of acute myocardial infarction.
Coronary artery disease (CAD), also called coronary heart disease (CHD), or ischemic heart disease (IHD), [13] is a type of heart disease involving the reduction of blood flow to the cardiac muscle due to a build-up of atheromatous plaque in the arteries of the heart. [5] [6] [14] It is the most common of the cardiovascular diseases. [15]
Myocardial infarction is a common presentation of coronary artery disease. The World Health Organization estimated in 2004, that 12.2% of worldwide deaths were from ischemic heart disease; [146] with it being the leading cause of death in high- or middle-income countries and second only to lower respiratory infections in lower-income countries ...
It is often a sign of myocardial ischemia, of which coronary insufficiency is a major cause. Other ischemic heart diseases causing ST depression include: Subendocardial ischemia [3] or even infarction. [4] Subendocardial means non full thickness ischemia. In contrast, ST elevation is transmural (or full thickness) ischemia; Non Q-wave ...
Brief ischemia is associated with intense chest pain, known as angina. Severe ischemia can cause the heart muscle to die from hypoxia, such as during a myocardial infarction. Chronic moderate ischemia causes contraction of the heart to weaken, known as myocardial hibernation. [citation needed]
Reperfusion injury, sometimes called ischemia-reperfusion injury (IRI) or reoxygenation injury, is the tissue damage caused when blood supply returns to tissue (re-+ perfusion) after a period of ischemia or lack of oxygen (anoxia or hypoxia).
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