Search results
Results from the WOW.Com Content Network
Such a pathway can trigger the assembly of new molecules, such as a fat or protein. Pathways can also turn genes on and off, or spur a cell to move. [1] Some of the most common biological pathways are involved in metabolism, the regulation of gene expression and the transmission of signals. Pathways play a key role in advanced studies of genomics.
One best example that explains this phenomenon is mitogen-activated protein (MAP) kinase or ERK kinase. [1] MAP kinase not only plays an important function during growth of cell in the M phase phosphorylation cascade but also plays an important role during the sequence of signaling pathway. [2]
Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events. Proteins responsible for detecting stimuli are generally termed receptors, although in some cases the term sensor is used. [1]
While some receptors are cell-surface proteins, others are found inside cells. For example, estrogen is a hydrophobic molecule that can pass through the lipid bilayer of the membranes. As part of the endocrine system, intracellular estrogen receptors from a variety of cell types can be activated by estrogen produced in the ovaries. [citation ...
In cell biology, there are a multitude of signalling pathways. Cell signalling is part of the molecular biology system that controls and coordinates the actions of cells. Akt/PKB signalling pathway
Bottom, signal enters the cell nucleus and causes transcription of DNA, which is then expressed as protein. The MAPK/ERK pathway (also known as the Ras-Raf-MEK-ERK pathway) is a chain of proteins in the cell that communicates a signal from a receptor on the surface of the cell to the DNA in the nucleus of the cell.
Another example, sonic hedgehog signaling pathway, is one of the key regulators of embryonic development and is present in all bilaterians. [2] Signaling proteins give cells information to make the embryo develop properly. When the pathway malfunctions, it can result in diseases like basal cell carcinoma. [3]
A useful technique for assessing cellular localization uses genetic engineering to express in a cell a fusion protein or chimera consisting of the natural protein of interest linked to a "reporter" such as green fluorescent protein (GFP). [73] The fused protein's position within the cell can then be cleanly and efficiently visualized using ...