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  2. 6 Benefits of Taking Metformin (Besides Weight Loss) - AOL

    www.aol.com/6-benefits-taking-metformin-besides...

    Another small study on people without diabetes who were overweight or had obesity found that those taking metformin lost between 5.6 and 6.5 percent of their body weight. In contrast, the control ...

  3. Metformin - Wikipedia

    en.wikipedia.org/wiki/Metformin

    Metformin is distributed to (and appears to accumulate in) red blood cells, with a much longer elimination half-life: 17.6 hours [9] (reported as ranging from 18.5 to 31.5 hours in a single-dose study of nondiabetics).

  4. Biguanide - Wikipedia

    en.wikipedia.org/wiki/Biguanide

    The term "biguanidine" often refers specifically to a class of drugs that function as oral antihyperglycemic drugs used for diabetes mellitus or prediabetes treatment. [4] Examples include: Metformin - widely used in treatment of diabetes mellitus type 2; Phenformin - withdrawn from the market in most countries due to toxic effects

  5. Diabetes medication - Wikipedia

    en.wikipedia.org/wiki/Diabetes_medication

    Typical reduction in glycated hemoglobin (A1C) values for Metformin is 1.5–2.0% Metformin (Glucophage) may be the best choice for patients who also have heart failure, [10] but it should be temporarily discontinued before any radiographic procedure involving intravenous iodinated contrast, as patients are at an increased risk of lactic acidosis.

  6. Metformin slows colorectal cancer growth using microRNAs ...

    www.aol.com/metformin-slows-colorectal-cancer...

    A new cell study has shown the common type 2 diabetes medication metformin alters levels of microRNAs that target genes to slow down the growth and multiplication of colorectal cancer cells. The ...

  7. SGLT2 inhibitor - Wikipedia

    en.wikipedia.org/wiki/SGLT2_inhibitor

    Sotagliflozin (Inpefa) is a dual SGLT1/SGLT2 inhibitor approved by the US Food and Drug Administration (FDA) in May 2023, to reduce the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visit in adults with heart failure or type 2 diabetes, chronic kidney disease, and other cardiovascular risk factors.

  8. GLY-200 - Wikipedia

    en.wikipedia.org/wiki/GLY-200

    GLY-200 is an experimental drug that acts as a "polymeric mucin binding duodenal exclusion therapy"; it is developed by Glyscend Therapeutics for type 2 diabetes and obesity. It is intended to reversibly mimic the effects of gastric bypass without the need for surgery.

  9. Lobeglitazone - Wikipedia

    en.wikipedia.org/wiki/Lobeglitazone

    In the dose range, the mean half-life was 10.3 h. [2] Urine excretion was negligible amount in elimination of lobeglitazone in rat and human. [1] [2] The plasma protein binding of the drug is over 99%. [1] [6] The average blood-to-plasma concentration ratio was 0.636. The unbound fraction of lobeglitazone in microsomal incubation medium was 0.479.

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