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That left people concerned that phytoestrogens, like those found in soy, would put you at increased risk of breast cancer, as estrogen activity can act as a catalyst for cancer growth.
It is unclear if phytoestrogens have any effect on male physiology, with conflicting results about the potential effects of isoflavones originating from soy. [1] Some studies showed that isoflavone supplementation had a positive effect on sperm concentration, count, or motility , and increased ejaculate volume.
These side effects may occur in as many as 90% of men treated with bicalutamide monotherapy, [29] but gynecomastia is generally reported to occur in 70 to 80% of patients. [30] In the EPC trial, at a median follow-up of 7.4 years, breast pain and gynecomastia respectively occurred in 73.6% and 68.8% of men treated with 150 mg/day bicalutamide ...
Gynecomastia is thought to be caused by an altered ratio of estrogens to androgens mediated by an increase in estrogen action, a decrease in androgen action, or a combination of these two factors. [7] Estrogen and androgens have opposing actions on breast tissue: estrogens stimulate proliferation while androgens inhibit proliferation.
List of side effects of estradiol which may occur as a result of its use or have been associated with estrogen and/or progestogen therapy includes: [1] [2]. Gynecological: changes in vaginal bleeding, dysmenorrhea, increase in size of uterine leiomyomata, vaginitis including vaginal candidiasis, changes in cervical secretion and cervical ectropion, ovarian cancer, endometrial hyperplasia ...
Side effects of EEs include nausea, breast tension, edema, and breakthrough bleeding among others. [8] It is an estrogen, or an agonist of the estrogen receptors, the biological target of estrogens like estradiol. [5] [3] [4] EEs are a prodrug mainly of estradiol and to a lesser extent of equilin. [5] EEs were introduced for medical use by 1970 ...
Side effects of HDE specific to men may include gynecomastia (breast development), feminization and demasculinization in general (e.g., reduced body hair, decreased muscle mass and strength, feminine changes in fat mass and distribution, and reduced penile and testicular size), and sexual dysfunction (e.g., reduced libido and erectile dysfunction).
Other side effects of estrogens include an increased risk of blood clots, cardiovascular disease, and, when combined with most progestogens, breast cancer. [1] In men, estrogens can cause breast development, feminization, infertility, low testosterone levels, and sexual dysfunction among others.