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Polycystic liver disease (PLD) usually describes the presence of multiple cysts scattered throughout normal liver tissue. [1] PLD is commonly seen in association with autosomal-dominant polycystic kidney disease , with a prevalence of 1 in 400 to 1000, and accounts for 8–10% of all cases of end-stage renal disease . [ 2 ]
Only 30% of cysts disappear with medical treatment alone. Albendazole is preferred twice a day for 1–5 months. [39] An alternative to albendazole is mebendazole for at least 3 to 6 months. Surgery is indicated for bigger liver cysts (> 10 cm), cysts at risk of rupture and/or complicated cysts.
Echinococcal cysts are slow growing, [3] but can cause clinical symptoms in humans and be life-threatening. [4] Cysts may not initially cause symptoms, in some cases for many years. [3] Symptoms developed depend on location of the cyst, but most occur in the liver, lungs, or both. [4]
Of the worms, the cestode Echinococcus granulosus, also known as the dog tapeworm, infects the liver and forms characteristic hepatic hydatid cysts. [34] The liver flukes Fasciola hepatica and Clonorchis sinensis live in the bile ducts and cause progressive hepatitis and liver fibrosis. [34]
Peliosis hepatis is an uncommon vascular condition characterised by multiple, randomly distributed, blood-filled cavities throughout the liver.The size of the cavities usually ranges between a few millimetres and 3 cm in diameter. [1]
The most frequent forms are metastatic malignant neoplasm of liver) liver cell carcinoma hepatocellular carcinoma; hepatoma; cholangiocarcinoma; hepatoblastoma; angiosarcoma of liver; Kupffer cell sarcoma; other sarcomas of liver; Benign neoplasm of liver include hepatic hemangiomas, hepatic adenomas, and focal nodular hyperplasia (FNH).
Numerous little cysts with ringdown artefacts. Laboratory findings include high transaminase levels, raised gamma-glutamyl transferase or alkaline phosphatase levels, increased C-reactive protein , hypoalbuminemia , and hematologic abnormalities like thrombocytopenia , leukopenia , leukocytosis , and anemia .
There is an increased risk of cancer in the wall of the cyst. [citation needed] In older individuals, choledochal cysts are more likely to cause abdominal pain and intermittent episodes of jaundice and occasionally cholangitis (inflammation within the bile ducts caused by the spread of bacteria from the intestine into the bile ducts).