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In August 2020, the U.S. Food and Drug Administration (FDA) became aware of nitrosamine impurities in certain samples of rifampin. [61] The FDA and manufacturers are investigating the origin of these impurities in rifampin, and the agency is developing testing methods for regulators and industry to detect the 1-methyl-4-nitrosopiperazine (MNP ...
In non-resistant TB, rifampin binds the beta subunit of RNA polymerase and disrupts transcription elongation. Mutation in the rpoB gene changes the sequence of amino acids and eventual conformation, or arrangement, of the beta subunit. In this case, rifampin can no longer bind or prevent transcription, and the bacterium is resistant. [19] [20]
The rifamycin group includes the classic rifamycin drugs as well as the rifamycin derivatives rifampicin (or rifampin), rifabutin, rifapentine, rifalazil and rifaximin. Rifamycin, sold under the trade name Aemcolo, is approved in the United States for treatment of travelers' diarrhea in some circumstances. [1] [2] [3]
Rifapentine in pregnant women has not been studied, but animal reproduction studies have resulted in fetal harm and were teratogenic. If rifapentine or rifampin are used in late pregnancy, coagulation should be monitored due to a possible increased risk of maternal postpartum hemorrhage and infant bleeding. [2]
The other traditional medicine that is also practiced in Vietnam is traditional Chinese medicine (Trung Y), also known as Northern Herbology (Thuốc Bắc). [ 1 ] [ 2 ] Thuốc Nam is one of two kinds of folk remedies known to villagers, the other being the traditional exercise dưỡng sinh .
President Ngo Dinh Diem and family at his home in Hue (Central Viet Nam).jpg; President Ngo Dinh Diem on an inspection tour 350 km from Saigon (December, 1956).jpg; Portrait of Ngô Đình Diệm, from the book Ngo Dinh Diem of Viet-Nam.jpg; President Ngo Dinh Diem with the troops who defeated the Binh-Xuyen at Rung-Sat (May, 1955).jpg
The Stieng people (Vietnamese: Xtiêng/Stiêng) are an ethnic group of Vietnam and Cambodia. They speak Stieng, a language in the Bahnaric group of the Mon–Khmer languages. Most Stieng live in Bình Phước Province (81,708 in 2009) [3] of the Southeast region of Vietnam.
Abridged Chronicles of Đại Việt) or Việt sử lược (chữ Hán: 越史略; lit. Abridged Chronicles of Viet ) is an historical text that was compiled during the Trần dynasty . The three-book work was finished around 1377 and covers the history of Vietnam from the reign of Triệu Đà to the collapse of the Lý dynasty . [ 1 ]