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In August 2020, the U.S. Food and Drug Administration (FDA) became aware of nitrosamine impurities in certain samples of rifampin. [62] The FDA and manufacturers are investigating the origin of these impurities in rifampin, and the agency is developing testing methods for regulators and industry to detect the 1-methyl-4-nitrosopiperazine (MNP ...
The rifamycin group includes the classic rifamycin drugs as well as the rifamycin derivatives rifampicin (or rifampin), rifabutin, rifapentine, rifalazil and rifaximin. Rifamycin, sold under the trade name Aemcolo, is approved in the United States for treatment of travelers' diarrhea in some circumstances. [1] [2] [3]
Mount Sinai Journal of Medicine: Medicine: John Wiley & Sons: English: 1934–2012 Movement Disorders: Neurology: Wiley-Liss: English: 1986–present Myanmar Medical Journal: Medicine: Myanmar Medical Association: English: 1953–present Nano Biomedicine and Engineering: Medicine: Open-Access House of Science and Technology: English: 2009–present
Management of tuberculosis refers to techniques and procedures utilized for treating tuberculosis (TB), or simply a treatment plan for TB.. The medical standard for active TB is a short course treatment involving a combination of isoniazid, rifampicin (also known as Rifampin), pyrazinamide, and ethambutol for the first two months.
This page was last edited on 5 November 2023, at 03:42 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.
In non-resistant TB, rifampin binds the beta subunit of RNA polymerase and disrupts transcription elongation. Mutation in the rpoB gene changes the sequence of amino acids and eventual conformation, or arrangement, of the beta subunit. In this case, rifampin can no longer bind or prevent transcription, and the bacterium is resistant. [19] [20]
Richard Smith, the former editor of the medical journal the BMJ, has been critical of many of the aspects of modern-day medical journal publishing. [5] [12] Critics of medical publishing have argued that problems related to gaming of citation and authorship are prevalent in the field, as many authors did not actually contribute to the articles that their names are on, many contributors to the ...
This page was last edited on 5 November 2023, at 03:42 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.