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Bicillin L-A® is the first-line recommended treatment for syphilis and the only recommended treatment option for some patients. CDC continues to monitor the situation and will post updates as needed.
RECOMMENDATIONS FOR TREATMENT OF SYPHILIS. The first eight recommendations (in sections 4.1 and 4.2) apply to adults and adolescents (10–19 years of age), including people living with HIV, key populations (including sex workers, men who have sex with men and transgender persons), and pregnant women. Specific recommendations have also been ...
Infants and children aged ≥1 month with primary and secondary syphilis should be managed by a pediatric infectious disease specialist and evaluated for sexual abuse (e.g., through consultation with child protective services) (see Sexual Assault or Abuse of Children).
2021 STI Treatment Guidelines provide CDC’s most current evidence-based recommendations for preventing, diagnosing and treating people who have, or are at risk for, STIs. Includes regimens, evidence tables, wall chart, and pocket guide.
These guidelines provide updated, evidence-informed clinical and practical recommendations on the case management of people with symptoms of sexually transmitted infections (STIs) and support countries in updating their national guidelines for the case management of people with symptoms of STIs.
These guidelines provide updated treatment recommendations for treatment of Treponema pallidum (syphilis) based on the most recent evidence. They form one of several modules of guidelines for specific STIs.
t recommendations for Treponema pallidum and congenital syphilis. The recommendations summarized in Table 1 apply to all adults and adolescents (10–19 years of age), including pregnant women, people living with HIV, people who are immunocompromised and key populations, including sex.