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Clark's rule. Clark's rule is a medical term referring to a mathematical formula used to calculate the proper dosage of medicine for children aged 2–17 based on the weight of the patient and the appropriate adult dose. [1] The formula was named after Cecil Belfield Clarke (1894–1970), a Barbadian physician who practiced throughout the UK ...
The Broselow Tape, also called the Broselow pediatric emergency tape, is a color-coded length-based tape measure that is used throughout the world for pediatric emergencies. The Broselow Tape relates a child's height as measured by the tape to their weight to provide medical instructions including medication dosages, the size of the equipment ...
For children, intravenous patient-controlled analgesia (IV-PCA) can be used when parenteral administration is preferred. [38] IV-PCA allows for consistent opioid levels, which can be a better alternative to scheduled intramuscular injections. [1] In addition, studies have shown that children as young as 6 years old can use the IV-PCA correctly ...
Body surface area. In physiology and medicine, the body surface area (BSA) is the measured or calculated surface area of a human body. For many clinical purposes, BSA is a better indicator of metabolic mass than body weight because it is less affected by abnormal adipose mass. Nevertheless, there have been several important critiques of the use ...
In pharmacology, the volume of distribution (V D, also known as apparent volume of distribution, literally, volume of dilution[1]) is the theoretical volume that would be necessary to contain the total amount of an administered drug at the same concentration that it is observed in the blood plasma. [2] In other words, it is the ratio of amount ...
Maintenance dose. In pharmacokinetics, a maintenance dose is the maintenance rate [mg/h] of drug administration equal to the rate of elimination at steady state. This is not to be confused with dose regimen, which is a type of drug therapy in which the dose [mg] of a drug is given at a regular dosing interval on a repetitive basis.
A loading dose is most useful for drugs that are eliminated from the body relatively slowly, i.e. have a long systemic half-life. Such drugs need only a low maintenance dose in order to keep the amount of the drug in the body at the appropriate therapeutic level, but this also means that, without an initial higher dose, it would take a long ...
Common mosquito repellents that people apply on their skin have either DEET or picaridin, Yancey says. Also consider treating clothing with 0.5% permethrin to help ward away mosquitos especially ...