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When investigating the selection of the polymer for biomedical applications, important criteria to consider are; The mechanical properties must match the application and remain sufficiently strong until the surrounding tissue has healed. The degradation time must match the time required. It does not invoke a toxic response.
All biodegradable polymers should be stable and durable enough for use in their particular application, but upon disposal they should easily break down. [citation needed] Polymers, specifically biodegradable polymers, have extremely strong carbon backbones that are difficult to break, such that degradation often starts from the end-groups.
Polyanhydrides are a class of biodegradable polymers characterized by anhydride bonds that connect repeat units of the polymer backbone chain. Their main application is in the medical device and pharmaceutical industry. In vivo, polyanhydrides degrade into non-toxic diacid monomers that can be metabolized and eliminated from the body. Owing to ...
This material can be used for biodegradable, homogeneous, dense films that are very useful in the biomedical field. Alginate: Alginate is the most copious marine natural polymer derived from brown seaweed. Alginate biopolymer applications range from packaging, textile and food industry to biomedical and chemical engineering.
The application of biodegradable synthetic polymers began in the later 1960s. [38] Biodegradable materials have an advantage over other materials, as they have lower risk of harmful effects long term. In addition to ethical advancements using biodegradable materials, they also improve biocompatibility for materials used for implantation. [38]
The biodegradable polymers used in biomedical applications typically consist of hydrolyzable esters and hydrazones. These molecules, upon external stimulation, go on to be cleaved and broken down. The cleaving activation process can be achieved through use of an acidic environment, increasing the temperature, or by use of enzymes. [82]
Other biomedical applications include the use of biodegradable, elastic shape-memory polymers. Biodegradable implant materials can now be used for minimally invasive surgical procedures through degradable thermoplastic polymers. These polymers are now able to change their shape with increase of temperature, causing shape memory capabilities as ...
Biodegradable polymers are widely used materials for many biomedical and pharmaceutical applications. These polymers are considered very promising for controlled drug delivery devices. Biodegradable polymers also offer great potential for wound management, orthopaedic devices, dental applications and tissue engineering. Not like non ...
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