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All biodegradable polymers should be stable and durable enough for use in their particular application, but upon disposal they should easily break down. [citation needed] Polymers, specifically biodegradable polymers, have extremely strong carbon backbones that are difficult to break, such that degradation often starts from the end-groups.
[2] [3] In the field of controlled drug delivery, biodegradable polymers offer tremendous potential either as a drug delivery system alone or in conjunction to functioning as a medical device. [4] In the development of applications of biodegradable polymers, the chemistry of some polymers including synthesis and degradation is reviewed below.
This material can be used for biodegradable, homogeneous, dense films that are very useful in the biomedical field. Alginate: Alginate is the most copious marine natural polymer derived from brown seaweed. Alginate biopolymer applications range from packaging, textile and food industry to biomedical and chemical engineering.
Polyanhydrides are a class of biodegradable polymers characterized by anhydride bonds that connect repeat units of the polymer backbone chain. Their main application is in the medical device and pharmaceutical industry. In vivo, polyanhydrides degrade into non-toxic diacid monomers that can be metabolized and eliminated from the body. Owing to ...
The application of biodegradable synthetic polymers began in the later 1960s. [38] Biodegradable materials have an advantage over other materials, as they have lower risk of harmful effects long term. In addition to ethical advancements using biodegradable materials, they also improve biocompatibility for materials used for implantation. [38]
The biodegradable polymers used in biomedical applications typically consist of hydrolyzable esters and hydrazones. These molecules, upon external stimulation, go on to be cleaved and broken down. The cleaving activation process can be achieved through use of an acidic environment, increasing the temperature, or by use of enzymes. [82]
Biodegradable polymers are classified into three groups: medical, ecological, and dual application, while in terms of origin they are divided into two groups: natural and synthetic. [18] The Clean Technology Group is exploiting the use of supercritical carbon dioxide , which under high pressure at room temperature is a solvent that can use ...
Biodegradable polymers also offer great potential for wound management, orthopaedic devices, dental applications and tissue engineering. Not like non biodegradable polymers, they won't require a second step of a removal from body. Biodegradable polymers will break down and are absorbed by the body after they served their purpose. Since 1960 ...