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Endolymphatic hydrops is a disorder of the inner ear. It consists of an excessive build-up of the endolymph fluid, which fills the hearing and balance structures of the inner ear. Endolymph fluid, which is partly regulated by the endolymph sac, flows through the inner ear and is critical to the function of all sensory cells in the inner ear.
Ototoxicity of gentamicin can be exploited to treat some individuals with Ménière's disease by destroying the inner ear, which stops the vertigo attacks but causes permanent deafness. [19] Due to the effects on mitochondria, certain inherited mitochondrial disorders result in increased sensitivity to the toxic effects of aminoglycosides.
The inner ear (internal ear, auris interna) is the innermost part of the vertebrate ear. In vertebrates , the inner ear is mainly responsible for sound detection and balance. [ 1 ] In mammals , it consists of the bony labyrinth , a hollow cavity in the temporal bone of the skull with a system of passages comprising two main functional parts: [ 2 ]
Fluid in the ear means a buildup of mucus, or fluid, behind the eardrum. A healthy middle ear is filled with air, not fluid. Having fluid in there can be uncomfortable, serve as a breeding ground ...
Cochlear hydrops preferentially affects the apex of the cochlea where low-frequency sounds are interpreted. Due to the fluid imbalance in this area, parts of the cochlea are stretched or under more tension than usual, which can lead to distortions of sound, changes in pitch perception, or hearing loss, all usually in the low frequencies.
Earwax helps protect the ear by trapping dust and other foreign particles that could filter through and damage the eardrum. [5] Normally, earwax moves toward the opening of the ear and falls out or is washed away, but sometimes excessive earwax can gather and become hard to remove. This is referred to as excessive earwax or impacted cerumen. [21]
Perilymph and endolymph have unique ionic compositions suited to their functions in regulating electrochemical impulses of hair cells necessary for hearing. The electric potential of endolymph is ~80-90 mV more positive than perilymph due to a higher concentration of potassium cations (K +) in endolymph and higher sodium (Na +) in perilymph. [4]
IEDCS and inner ear barotrauma (IEBt) are the inner ear injuries associated with ambient pressure diving, both of which manifest as cochleovestibular symptoms. The similarity of symptoms makes differential diagnosis difficult, which can delay appropriate treatment or lead to inappropriate treatment.
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