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  2. Serotonin–norepinephrine–dopamine reuptake inhibitor

    en.wikipedia.org/wiki/Serotonin–norepinephrine...

    The original monoamine hypothesis postulates that depression is caused by a deficiency or imbalances in the monoamine neurotransmitters (5-HT, NE, and DA). This has been the central topic of depression research for approximately the last 50 years; [ 12 ] [ 192 ] it has since evolved into the notion that depression arises through alterations in ...

  3. Biology of depression - Wikipedia

    en.wikipedia.org/wiki/Biology_of_depression

    The biology of depression is the attempt to identify a biochemical origin of depression, as opposed to theories that emphasize psychological or situational causes. Scientific studies have found that different brain areas show altered activity in humans with major depressive disorder (MDD) . [ 1 ]

  4. Neurogenesis hypothesis of depression - Wikipedia

    en.wikipedia.org/wiki/Neurogenesis_hypothesis_of...

    While depression is a complex condition with many factors involved, it is commonly attributed to an imbalance of several key monoamine neurotransmitters, including serotonin, dopamine and norepinephrine. This monoamine hypothesis of depression is popular because of the simplicity of the explanation. [4]

  5. Depression is likely not caused by a chemical imbalance in ...

    www.aol.com/depression-likely-not-caused...

    For years, a chemical imbalance of serotonin has been widely viewed as the culprit for depression, resulting in the widespread use of antidepressants. The study published this week in the journal…

  6. Bipolar Disorder: 4 Types & What You Need to Know About Them

    www.aol.com/bipolar-disorder-4-types-know...

    There may also be imbalances in mood-regulating neurotransmitters (brain chemicals) like dopamine and serotonin. But this isn’t well understood, either. But this isn’t well understood, either.

  7. Neurotrophic hypothesis of depression - Wikipedia

    en.wikipedia.org/wiki/Neurotrophic_hypothesis_of...

    The neurotrophic hypothesis of depression [1] proposes that major depressive disorder (MDD) is caused, at least partly, by impaired neurotrophic support.Neurotrophic factors (also known as neurotrophins) are a family of closely related proteins which regulate the survival, development, and function of neurons in both the central and peripheral nervous systems.

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