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Side effects can differ within the drug class due to differences in metabolism and pharmacology. For example, long-acting benzodiazepines have problems of drug accumulation especially in the elderly or those with liver disease, and shorter-acting benzodiazepines have a higher risk of more severe withdrawal symptoms.
The nonbenzodiazepines, also called benzodiazepine-like drugs, are a class of psychoactive drugs pharmacologically resembling the benzodiazepines, with similar benefits, side effects and risks, despite having dissimilar or entirely different chemical structures.
Sonata – a non-benzodiazepine hypnotic Spravato ( esketamine ) – a rapid-acting antidepressant of the NMDA receptor antagonist class; enantiomer of ketamine Stelazine ( trifluoperazine ) – an antipsychotic used in the treatment of psychotic disorders, anxiety , and nausea caused by chemotherapy [ 2 ]
Benzodiazepines can cause side effects, including some that may affect your alertness, physical health and daily life. Common side effects of benzodiazepines include: Drowsiness.
Common side effects include headache, dry mouth, nausea, and dizziness. [5] Severe side effects may include suicidal thoughts, hallucinations, and angioedema. [5] Rapid decreasing of the dose may result in withdrawal. [5] Eszopiclone is classified as a nonbenzodiazepine or Z-drug and a sedative and hypnotic of the cyclopyrrolone group. [7]
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It works by increasing GABA effects in the central nervous system by binding to GABA A receptors at the same location as benzodiazepines. [11] It generally has a half-life of two to three hours. [11] This, however, is increased in those with liver problems. [11] Zolpidem was approved for medical use in the United States in 1992.
It’s personal, and some people will naturally be more sensitive to side effects than others, like they would with any other medication, says Dr. Gold. ... (like benzodiazepines, for example) and ...