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  2. Keratin - Wikipedia

    en.wikipedia.org/wiki/Keratin

    Microscopy of keratin filaments inside cells. Keratin (/ ˈ k ɛr ə t ɪ n / [1] [2]) is one of a family of structural fibrous proteins also known as scleroproteins. Alpha-keratin (α-keratin) is a type of keratin found in vertebrates.

  3. Keratinocyte - Wikipedia

    en.wikipedia.org/wiki/Keratinocyte

    Keratinization is part of the physical barrier formation (cornification), in which the keratinocytes produce more and more keratin and undergo terminal differentiation. The fully cornified keratinocytes that form the outermost layer are constantly shed off and replaced by new cells.

  4. List of keratins expressed in the human integumentary system

    en.wikipedia.org/wiki/List_of_keratins_expressed...

    Suprabasal epidermis of skin 2 (2e) Granular layer: 3: Cornea: 4: Suprabasal epidermis of mucosa 5: Basal layer: 6a: Suprabasal palmoplantar skin 6b: Basal palmoplantar skin Nail bed Hair follicle 7: 8: 9: Suprabasal palmoplantar skin 10: Suprabasal epidermis 11: 12: Cornea: 13: Suprabasal epidermis of mucosa 14: Basal layer: 15: Basal layer of ...

  5. Keratohyalin - Wikipedia

    en.wikipedia.org/wiki/Keratohyalin

    Keratohyalin is a protein structure found in cytoplasmic granules of the keratinocytes in the stratum granulosum of the epidermis.Keratohyalin granules (KHG) mainly consist of keratin, profilaggrin, [1] loricrin [2] and trichohyalin proteins which contribute to cornification or keratinization, the process of the formation of epidermal cornified cell envelope.

  6. Keratin 1 - Wikipedia

    en.wikipedia.org/wiki/Keratin_1

    16678 Ensembl ENSG00000167768 ENSMUSG00000046834 UniProt P04264 P04104 RefSeq (mRNA) NM_006121 NM_008473 RefSeq (protein) NP_006112 NP_032499 Location (UCSC) Chr 12: 52.67 – 52.68 Mb Chr 15: 101.75 – 101.76 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Keratin 1 is a Type II intermediate filament (IFs) of the intracytoplasmatic cytoskeleton. Is co-expressed with and binds to ...

  7. Parakeratosis - Wikipedia

    en.wikipedia.org/wiki/Parakeratosis

    Parakeratosis is a mode of keratinization characterized by the retention of nuclei in the stratum corneum. [1] In mucous membranes , parakeratosis is normal. [ 2 ] In the skin, this process leads to the abnormal replacement of annular squames with nucleated cells.

  8. Skin sloughing - Wikipedia

    en.wikipedia.org/wiki/Skin_sloughing

    Atopic dermatitis (or eczema) is the most common inflammatory skin disease. Skin may slough in a peeling fashion. Contact dermatitis arises from contact with a skin irritant. The ensuing irritation can cause sores and skin sloughing. and Seborrheic dermatitis which is associated with skin shedding through dandruff.

  9. HaCaT - Wikipedia

    en.wikipedia.org/wiki/HaCaT

    HaCaT is a spontaneously transformed aneuploid immortal keratinocyte cell line from adult human skin, [1] [2] widely used in scientific research. [3] HaCaT cells are utilized for their high capacity to differentiate and proliferate in vitro. [4]