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The research began with the selection of 22 subjects from a veterans' orphanage in Iowa. None were told the intent of the research, and they believed that they were to receive speech therapy. The study was trying to induce stuttering in healthy children. The experiment became national news in the San Jose Mercury News in 2001, and a book was ...
Joachim Boldt (Germany), an anesthesiologist formerly based at the Justus Liebig University Giessen, was stripped of his professorship and criminally investigated for forgery in his research studies. [17] As of 2024, Boldt has had 220 of his research publications retracted, and 10 others have received an expression of concern. [18] [19]
The San Antonio Contraceptive Study was a clinical research study published in 1971 about the side effects of oral contraceptives. Women coming to a clinic in San Antonio, Texas to prevent pregnancies were not told they were participating in a research study or receiving placebos. Ten of the women became pregnant while on placebos. [183] [184 ...
Medical ethics is an applied branch of ethics which analyzes the practice of clinical medicine and related scientific research. [1] Medical ethics is based on a set of values that professionals can refer to in the case of any confusion or conflict. These values include the respect for autonomy, non-maleficence, beneficence, and justice. [2]
Beneficence is a concept in research ethics that states that researchers should have the welfare of the research participant as a goal of any clinical trial or other research study. The antonym of this term, maleficence , describes a practice that opposes the welfare of any research participant.
Examples include American abuses during Project MKUltra and the Tuskegee syphilis experiments, and the mistreatment of indigenous populations in Canada and Australia. The Declaration of Helsinki, developed by the World Medical Association (WMA), is widely regarded as the cornerstone document on human research ethics. [1] [2] [3]
It is the violation of scientific integrity: violation of the scientific method and of research ethics in science, including in the design, conduct, and reporting of research. A Lancet review on Handling of Scientific Misconduct in Scandinavian countries provides the following sample definitions, [1] reproduced in The COPE report 1999: [2]
Research integrity or scientific integrity became an autonomous concept within scientific ethics in the late 1970s. In contrast with other forms of ethical misconducts, the debate over research integrity is focused on "victimless offence" that only hurts "the robustness of scientific record and public trust in science". [3]