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Permethrin does not present any notable genotoxicity or immunotoxicity in humans and farm animals, but is classified by the EPA as a likely human carcinogen when ingested, based on reproducible studies in which mice fed permethrin developed liver and lung tumors. [35] A 2018 review failed to link permethrin exposure in humans to cancer. [36]
Permethrin is also the active ingredient in insecticides used against the Small hive beetle, which is a parasite of the beehive in the temperate climate regions. Highly toxic Cypermethrin [55] Ammo, Demon, Raid, Viper Pyrethroid: Less than 2 hours Cypermethrin is found in many household ant and cockroach killers, including Raid and ant chalk ...
Cypermethrin is moderately toxic through skin contact or ingestion. It may cause irritation to the skin and eyes. Symptoms of dermal exposure include numbness, tingling, itching, burning sensation, loss of bladder control, incoordination, seizures and possible death. Pyrethroids may adversely affect the central nervous system.
As of 2019 Raid Ant & Roach Killer contains pyrethroids, imiprothrin, and cypermethrin; [3] other products contain tetramethrin and prallethrin as active ingredients. [4] Raid Flying Insect Killer, a spray, uses piperonyl butoxide and D-phenothrin. [5] The brand was sold as Ridsect for Malaysian market.
By 1974, the Rothamsted team had discovered a second generation of more persistent compounds notably: permethrin, cypermethrin and deltamethrin. They are substantially more resistant to degradation by light and air, thus making them suitable for use in agriculture , but they have significantly higher mammalian toxicities.
Permethrin, sulfur, lindane, dicophane, benzyl benzoate, ivermectin and crotamiton are well known ectoparasiticides. [2] Additionally, ectoparasiticides have been used to safely contaminate rhinoceros horns with hopes of it deterring the demand for these horns on the black market.
Insecticides such as pyrethroids (e.g. permethrin, bifenthrin, cyfluthrin) have been used for control, [7] but this approach is often considered counter-productive due to mortality of mealybug natural enemies.
Mirex is a stomach insecticide, meaning that it must be ingested by the organism in order to poison it. The insecticidal use was focused on Southeastern United States to control fire ants. Approximately 250,000 kg of mirex were applied to fields between 1962 and 1975 (US NRC, 1978).
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