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Protein precipitation is widely used in downstream processing of biological products in order to concentrate proteins and purify them from various contaminants. For example, in the biotechnology industry protein precipitation is used to eliminate contaminants commonly contained in blood. [ 1 ]
Ammonium sulfate precipitation is a useful technique as an initial step in protein purification because it enables quick, bulk precipitation of cellular proteins. [4] It is also often employed during the later stages of purification to concentrate protein from dilute solution following procedures such as gel filtration .
Margaret Belle (Oakley) Dayhoff (March 11, 1925 – February 5, 1983) was an American Biophysicist and a pioneer in the field of bioinformatics. [1] Dayhoff was a professor at Georgetown University Medical Center and a noted research biochemist at the National Biomedical Research Foundation, where she pioneered the application of mathematics and computational methods to the field of biochemistry.
Salting out (also known as salt-induced precipitation, salt fractionation, anti-solvent crystallization, precipitation crystallization, or drowning out) [1] is a purification technique that utilizes the reduced solubility of certain molecules in a solution of very high ionic strength.
The protein manufacturing cost remains high and there is a growing demand to develop cost efficient and rapid protein purification methods. Understanding of the different protein purification methods and optimizing the downstream processing are critical to minimize production costs while maintaining the quality of acceptable standards of homogeneity. [2]
In 2011, a Wiki Governance Team was set up, which in 2015 was replaced by the Governance Council whose role was to oversee the direction and management of the Research Wiki. [11] [12] In late March 2016, the wiki was transitioned to WikiMedia 1.23.10, a newer, more stable platform which required less maintenance from FamilySearch computer ...
A study on trees associated with Late Pleistocene/Early Holocene campsites from the Atacama Desert is published by Ugalde et al. (2024), who report evidence of the first people living in the area locating their homes under the tree canopy at two sites, and find that the early people in the area spared the most abundant and resilient tree ...
Molly (name) or Mollie, a female given name, including a list of persons and characters with the name Molly Pitcher, one of several American women believed to have helped fight against British forces during the American Revolution