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Drusen, from the German word for node or geode (singular, "Druse"), are tiny yellow or white accumulations of extracellular material that build up between Bruch's membrane and the retinal pigment epithelium of the eye. The presence of a few small ("hard") drusen is normal with advancing age, and most people over 40 have some hard drusen. [1]
Dietary antioxidant vitamins, minerals, and carotenoids do not appear to affect the onset; [5] however, dietary supplements may slow the progression in those who already have the disease. [ 5 ] Age-related macular degeneration is a main cause of central blindness among the working-aged population worldwide. [ 6 ]
Age-Related Macular Degeneration is a degenerative maculopathy associated with progressive sight loss. It is characterised by changes in pigmentation in the Retinal Pigment Epithelium, the appearance of drusen on the retina of the eye and choroidal neovascularization. AMD has two forms; 'dry' or atrophic/non-exudative AMD, and 'wet' or ...
Dry macular degeneration develops when tiny yellow protein deposits called drusen form under the macula. ... Depending on whether the sufferer has the dry or wet version of the disease, treatments ...
Layers of the eye, with the choroid labelled. Choroidal neovascularization (CNV) is the creation of new blood vessels in the choroid layer of the eye.Choroidal neovascularization is a common cause of neovascular degenerative maculopathy (i.e. 'wet' macular degeneration) [1] commonly exacerbated by extreme myopia, malignant myopic degeneration, or age-related developments.
Geographic atrophy (GA), also known as atrophic age-related macular degeneration (AMD) or advanced dry AMD, is an advanced form of age-related macular degeneration that can result in the progressive and irreversible loss of retinal tissue (photoreceptors, retinal pigment epithelium, choriocapillaris) which can lead to a loss of visual function over time.
Stargardt disease is the most common inherited single-gene retinal disease. [1] In terms of the first description of the disease, [ 2 ] it follows an autosomal recessive inheritance pattern, which has been later linked to bi-allelic ABCA4 gene variants (STGD1).
Heart Health: This area is less studied, but growing evidence shows that vitamin D could protect against cardiovascular disease. When estrogen levels drop during menopause, women’s risk of heart ...