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An osteocyte, an oblate shaped type of bone cell with dendritic processes, is the most commonly found cell in mature bone. It can live as long as the organism itself. [1] The adult human body has about 42 billion of them. [2] Osteocytes do not divide and have an average half life of 25 years.
Diagram of a typical long bone showing both cortical (compact) and cancellous (spongy) bone. Haversian canals [i] (sometimes canals of Havers, osteonic canals or central canals) are a series of microscopic tubes in the outermost region of bone called cortical bone. They allow blood vessels and nerves to travel through them to supply the osteocytes.
They usually run at obtuse angles to the Haversian canals (which run the length of the bone) and contain anastomosing vessels between haversian capillaries. They were named after German physiologist Alfred Volkmann (1800–1878). The perforating canals, with the blood vessels, provide energy and nourishing elements for osteons.
The dental canaliculi (sometimes called dentinal tubules) are the blood supply of a tooth. [4] Odontoblast process run in the canaliculi that transverse the dentin layer and are referred as dentinal tubules. [5] The number and size of the canaliculi decrease as the tubules move away from the pulp and toward the enamel or cementum.
In the hollow within bones are many other cell types of the bone marrow. Components that are essential for osteoblast bone formation include mesenchymal stem cells (osteoblast precursor) and blood vessels that supply oxygen and nutrients for bone formation. Bone is a highly vascular tissue, and active formation of blood vessel cells, also from ...
The periosteum is a membrane that covers the outer surface of all bones, [1] except at the articular surfaces (i.e. the parts within a joint space) of long bones. (At the joints of long bones the bone's outer surface is lined with "articular cartilage", a type of hyaline cartilage.) Endosteum lines the inner surface of the medullary cavity of ...
All bones possess larger or smaller foramina (openings) for the entrance of blood-vessels; these are known as the nutrient foramina, and are particularly large in the shafts of the larger long bones, where they lead into a nutrient canal, which extends into the medullary cavity. The nutrient canal (foramen) is directed away from the growing end ...
Unlike red and white blood cells, created by mitosis, platelets are shed from very large cells called megakaryocytes. [56] This process of progressive differentiation occurs within the bone marrow. After the cells are matured, they enter the circulation. [57] Every day, over 2.5 billion red blood cells and platelets, and 50–100 billion ...