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Muscle fatigue is when muscles that were initially generating a normal amount of force, then experience a declining ability to generate force. It can be a result of vigorous exercise, but abnormal fatigue may be caused by barriers to or interference with the different stages of muscle contraction. There are two main causes of muscle fatigue ...
The symptoms of rhabdomyolysis depend on its severity and whether kidney failure develops. Milder forms may not cause any muscle symptoms, and the diagnosis is based on abnormal blood tests in the context of other problems. More severe rhabdomyolysis is characterized by muscle pain, tenderness, weakness and swelling of the affected muscles. [10]
Diagnosis. Exertional rhabdomyolysis, the exercise-induced muscle breakdown that results in muscle pain/soreness, is commonly diagnosed using the urine myoglobin test accompanied by high levels of creatine kinase (CK). Myoglobin is the protein released into the bloodstream when skeletal muscle is broken down.
Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system's ability to readily detoxify the reactive intermediates or to repair the resulting damage. [ 1 ] Disturbances in the normal redox state of cells can cause toxic effects through the production of peroxides and free ...
Muscle aches and spasms (tetany), especially in infants who develop rickets, as a result of low calcium levels that occur with vitamin D deficiency. Muscle weakness. Painful walking. Weakness of ...
Definition. Hypoxemia refers to the low level of oxygen in blood, and the more general term hypoxia is an abnormally low oxygen content in any tissue or organ, or the body as a whole. [2] Hypoxemia can cause hypoxia (hypoxemic hypoxia), but hypoxia can also occur via other mechanisms, such as anemia. [4]
Hypoxia is a condition in which the body or a region of the body is deprived of adequate oxygen supply at the tissue level. [ 1 ] Hypoxia may be classified as either generalized, affecting the whole body, or local, affecting a region of the body. [ 2 ] Although hypoxia is often a pathological condition, variations in arterial oxygen ...
Metabolic myopathy. Metabolic myopathies are myopathies that result from defects in biochemical metabolism that primarily affect muscle. They are generally genetic defects (inborn errors of metabolism) that interfere with the ability to create energy, causing a low ATP reservoir within the muscle cell. [1][2] At the cellular level, metabolic ...