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Biguanide (/ b aɪ ˈ ɡ w ɒ n aɪ d /) is the organic compound with the formula HN(C(NH)NH 2) 2. It is a colorless solid that dissolves in water to give a highly basic solution. It is a colorless solid that dissolves in water to give a highly basic solution.
The lactic acidosis occurred only in patients with a buformin plasma level of greater than 0.60 μg/mL and was rare in patients with normal renal function. [19] [20] [21] In one report, the toxic oral dose was 329 ± 30 mg/day in 24 patients who developed lactic acidosis on buformin.
One study found that men with moderate-to-high levels of exhaustion had a 2.7-fold increased risk of heart attack within five years and a 2.25 higher risk within ten years. The study also found a ...
A cheeky little slice of cake here, a cookie there, or a nibble of chocolate every once in a while isn't the worst thing in the world. But according to new research, the buck stops at sugary drinks.
Polyaminopropyl biguanide (PAPB) is a polymer containing biguanide group connected with a three methylene (propyl) linker. The polymer is a propyl analogue of polyhexamethylene biguanide . The polymer display some antibacterial activity however much lower than PHMB.
A "prolific and chilling" sex abuser from Northern Ireland has been sentenced to 27 years in prison. David John Andrews, 55, with an address at Maghaberry Prison, pleaded guilty to 130 charges of ...
Later development of nontoxic, safe biguanides led to the long-used first-line diabetes control medicine metformin, introduced to Europe in the 1950s & United States in 1995 and now prescribed to over 17 million patients per year in the US. [14] [15] Guanidinium chloride [14] is a now-controversial adjuvant in treatment of botulism. Recent ...
The researchers analyzed historical data on childhood blood-lead levels, leaded gas use and U.S. population statistics, determining that more than 170 million Americans had "clinically concerning ...