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Eastell has pioneered new techniques for measuring calcium uptake and vitamin D conversion and is a leading expert in osteoporosis diagnosis, implementation of bone turnover markers and new osteoporosis treatments. [3] While at the Mayo Clinic, Eastell developed new non-radioactive methods for measuring how calcium was absorbed from the diet ...
Osteoporosis may also occur due to a number of diseases or treatments, including alcoholism, anorexia, hyperthyroidism, kidney disease, and surgical removal of the ovaries. Certain medications increase the rate of bone loss, including some antiseizure medications , chemotherapy , proton pump inhibitors , selective serotonin reuptake inhibitors ...
See also osteoporosis. In June 1992, the World Health Organization defined osteopenia. [48] [34] An osteoporosis epidemiologist at the Mayo Clinic who participated in setting the criterion in 1992 said "It was just meant to indicate the emergence of a problem", and noted that "It didn't have any particular diagnostic or therapeutic significance ...
Osteoporosis is the weakening of the bones due to progressive decrease in bone density. [13] In older patients, the low bone density of the spine is unable to support the weight of the body. This gives rise to CSM via vertebral compression fractures [14] promoting further compression of the spinal cord and nerve roots.
Bisphosphonates are used to treat osteoporosis, osteitis deformans (Paget's disease of the bone), bone metastasis (with or without hypercalcemia), multiple myeloma, and other conditions involving fragile, breakable bone. In osteoporosis and Paget's, the most popular first-line bisphosphonate drugs are alendronate and risedronate.
Senile osteoporosis has been recently recognized as a geriatric syndrome with a particular pathophysiology. There are different classification of osteoporosis: primary, in which bone loss is a result of aging and secondary, in which bone loss occurs from various clinical and lifestyle factors. [1]
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